• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Genetic regulation of N-acetyltransferase in target organs of arylamine tumors: homologous expression in human and hamster bladder and colon.

作者信息

Hein D W

机构信息

Department of Pharmacology, University of North Dakota School of Medicine, Grand Forks 58203.

出版信息

Proc West Pharmacol Soc. 1991;34:55-60.

PMID:1788341
Abstract
摘要

相似文献

1
Genetic regulation of N-acetyltransferase in target organs of arylamine tumors: homologous expression in human and hamster bladder and colon.
Proc West Pharmacol Soc. 1991;34:55-60.
2
Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus.在NAT2基因座同基因的叙利亚仓鼠结肠胞质溶胶中，单态性N-乙酰基转移酶（NAT1）和多态性N-乙酰基转移酶（NAT2）对N-羟基-2-氨基芴和N-羟基-2-乙酰氨基芴的代谢激活作用。
Cancer Res. 1993 Feb 1;53(3):509-14.
3
Polymorphic and monomorphic expression of arylamine carcinogen N-acetyltransferase isozymes in tumor target organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus.在多态性乙酰转移酶基因座同基因的叙利亚仓鼠肿瘤靶器官胞质溶胶中芳胺致癌物N - 乙酰转移酶同工酶的多态性和单态性表达
J Pharmacol Exp Ther. 1991 Nov;259(2):699-704.
4
Identification and kinetic characterization of acetylator genotype-dependent and -independent arylamine carcinogen N-acetyltransferases in hamster bladder cytosol.仓鼠膀胱细胞溶质中乙酰化酶基因型依赖性和非依赖性芳胺致癌物N-乙酰转移酶的鉴定及动力学特征分析
Drug Metab Dispos. 1989 May-Jun;17(3):231-7.
5
Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens.在多态性乙酰转移酶基因座（NAT2）构建叙利亚仓鼠同源系：芳胺致癌物的乙酰化基因型依赖性N-和O-乙酰化作用
Toxicol Appl Pharmacol. 1994 Jan;124(1):16-24. doi: 10.1006/taap.1994.1003.
6
Acetylator genotype-dependent expression of arylamine N-acetyltransferase and N-hydroxyarylamine O-acetyltransferase in Syrian inbred hamster intestine and colon. Identity with the hepatic acetylation polymorphism.叙利亚近交系仓鼠小肠和结肠中芳胺N - 乙酰基转移酶和N - 羟基芳胺O - 乙酰基转移酶的乙酰化酶基因型依赖性表达。与肝脏乙酰化多态性的一致性。
Drug Metab Dispos. 1990 Sep-Oct;18(5):680-5.
7
Luteolin induces N-acetylation and DNA adduct of 2-aminofluorene accompanying N-acetyltransferase activity and gene expression in human bladder cancer T24 cell line.木犀草素在人膀胱癌T24细胞系中诱导2-氨基芴的N-乙酰化和DNA加合物，并伴随N-乙酰转移酶活性和基因表达。
Anticancer Res. 2003 Jan-Feb;23(1A):355-62.
8
Purification of hepatic polymorphic arylamine N-acetyltransferase from homozygous rapid acetylator inbred hamster: identity with polymorphic N-hydroxyarylamine-O-acetyltransferase.从纯合快速乙酰化近交仓鼠中纯化肝多态性芳胺N-乙酰基转移酶：与多态性N-羟基芳胺-O-乙酰基转移酶相同。
Cancer Res. 1990 Dec 15;50(24):7942-9.
9
Polymorphic expression of acetyl coenzyme A-dependent arylamine N-acetyltransferase and acetyl coenzyme A-dependent O-acetyltransferase-mediated activation of N-hydroxyarylamines by human bladder cytosol.人膀胱胞质溶胶中乙酰辅酶A依赖性芳胺N-乙酰基转移酶的多态性表达以及乙酰辅酶A依赖性O-乙酰基转移酶介导的N-羟基芳胺激活作用
Cancer Res. 1989 May 1;49(9):2448-54.
10
Role of N-acetyltransferase phenotype in human susceptibility to bladder carcinogenic arylamines.N-乙酰转移酶表型在人类对膀胱致癌性芳基胺易感性中的作用。
Scand J Urol Nephrol. 1980;14(2):161-5. doi: 10.3109/00365598009179555.