Lawrence C, Cotton P B, Romagnuolo J, Payne K M, Rawls E, Hawes R H
Digestive Disease Center, Medical University of South Carolina, Charleston, South Carolina 29425, USA.
Endoscopy. 2007 Dec;39(12):1082-5. doi: 10.1055/s-2007-966815. Epub 2007 Sep 21.
Placing small stents in the pancreatic duct at endoscopic retrograde cholangiopancreatography reduces the risk of pancreatitis. However, this practice means that a second procedure might be required to remove the stent, and stents can also damage the duct. The aims of this study were to determine the frequency of spontaneous dislodgment and to assess the incidence of stent-induced ductal irregularities.
We performed a retrospective analysis of consecutive patients seen over a 3-year period (2001 - 2004) who had undergone placement of a 3-Fr pancreatic duct stent and in whom the fate of the stent had been documented. Radiographs were reviewed to determine stent passage at 30 days. If applicable, follow-up pancreatograms were reviewed to assess for stent-induced ductal abnormalities. Statistical analysis was performed using chi-squared and Fisher's exact tests for proportions, and 95 % binomial confidence intervals (CI) were calculated.
Records for 125 consecutive patients who had had 3-Fr pancreatic stents placed were reviewed. The stents had passed spontaneously within 30 days in 110/125 patients (88 %). In the remaining 15 patients (12 %, 95 % CI 6.9 % - 19 %), the stents were still present on follow-up radiographs after a median time of 36 days, (range 31 - 116 days). Stent length, pancreatic sphincterotomy, and pancreas divisum had no effect on the likelihood of spontaneous passage. No stent-induced ductal irregularities were observed.
Nearly 90 % of prophylactic 3-Fr pancreatic duct stents pass spontaneously within 30 days, and these stents were not observed to induce changes in the pancreatic duct.
在内镜逆行胰胆管造影术中于胰管内放置小支架可降低胰腺炎风险。然而,这种做法意味着可能需要进行第二次手术来取出支架,并且支架也可能损伤导管。本研究的目的是确定支架自发脱落的频率,并评估支架引起的导管不规则的发生率。
我们对连续3年(2001 - 2004年)接受3Fr胰管支架置入且记录了支架转归情况的患者进行了回顾性分析。复查X线片以确定30天时支架的通过情况。如果适用,复查随访胰管造影以评估支架引起的导管异常。使用卡方检验和Fisher精确检验对比例进行统计分析,并计算95%二项式置信区间(CI)。
对125例连续接受3Fr胰管支架置入的患者记录进行了复查。110/125例患者(88%)的支架在30天内自发通过。其余15例患者(12%,95%CI 6.9% - 19%)中,支架在中位时间36天(范围31 - 116天)后的随访X线片上仍存在。支架长度、胰括约肌切开术和胰腺分裂对自发通过的可能性没有影响。未观察到支架引起的导管不规则情况。
近90%的预防性3Fr胰管支架在30天内自发通过,且未观察到这些支架引起胰管改变。