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胸骨前密苏里天鹅颈导管的9年生存分析

A 9-year survival analysis of the presternal Missouri swan-neck catheter.

作者信息

Yerram Preethi, Gill Amandeep, Prowant Barbara, Saab Georges, Misra Madhukar, Whaley-Connell Adam

机构信息

University of Missouri--Columbia School of Medicine, Department of Internal Medicine, Division of Nephrology, Columbia, Missouri 65212, USA.

出版信息

Adv Perit Dial. 2007;23:90-3.

Abstract

Peritoneal dialysis (PD) catheter survival is challenging because of infection and malfunction. The swan-neck presternal catheter has a coiled intra-abdominal segment with a bead and a flanged cuff at the peritoneum; a titanium adapter joins the abdominal segment to the upper segment. The upper segment has two cuffs, one on either side of the presternal swan-neck segment. The present study evaluated the survival of Missouri presternal swan-neck PD catheters implanted at the University of Missouri--Columbia and followed at Dialysis Clinics, Inc., through 2006. Catheter type and insertion date were prospectively recorded. Survival was defined as the interval from insertion date to date of removal, censoring, or analysis. Catheters were censored for transplant, death, or transfer to another unit. A total of 131 presternal catheters were implanted in 129 patients. Mean patient age was 60.9 +/- 16.3 years. No catheters were removed during the first 3 months for either infection or technical problems. One catheter was removed at 6 months for malposition and another at 2 years for an external leak; all other catheter losses were attributable to peritonitis. Cumulative catheter survival was 93.5%, 82.5%, 63.9%, and 60.0% at 1, 2, 3, and 4 years respectively. The mean observation period was 19. 7 +/- 17.8 months, and the longest catheter survival was 87.5 months. New episodes of peritonitis were 91 in number, a rate of 1 episode per 28 patient-months. Although catheter survival exceeded the recommendation of better than 80% at 1 year, we noted a trend toward lower catheter survival and a higher peritonitis rate than were reported earlier in this series with a smaller number of catheters. That trend is partly explained by repeated episodes of peritonitis in 11 catheters; 8.5% of the patients experienced 40% of the peritonitis episodes.

摘要

由于感染和功能故障,腹膜透析(PD)导管的留存率面临挑战。鹅颈式胸骨前导管在腹腔内有一个带珠子的盘绕段,在腹膜处有一个带凸缘的袖套;一个钛制适配器将腹腔段与上段连接起来。上段有两个袖套,分别位于胸骨前鹅颈段的两侧。本研究评估了在密苏里大学哥伦比亚分校植入并在透析诊所公司随访至2006年的密苏里胸骨前鹅颈式PD导管的留存率。前瞻性记录导管类型和插入日期。留存率定义为从插入日期到拔除、审查或分析日期的间隔。导管因移植、死亡或转至另一单位而被审查。共129例患者植入了131根胸骨前导管。患者平均年龄为60.9±16.3岁。在前3个月内,没有导管因感染或技术问题而被拔除。1根导管在6个月时因位置不当被拔除,另1根在2年时因外部渗漏被拔除;所有其他导管丢失均归因于腹膜炎。1年、2年、3年和4年时导管的累积留存率分别为93.5%、82.5%、63.9%和60.0%。平均观察期为19.7±17.8个月,最长导管留存时间为87.5个月。腹膜炎新发病例有91例,发生率为每28个患者月1例。虽然导管1年留存率超过了优于80%的推荐值,但我们注意到与本系列早期报道的较少数量导管相比,导管留存率有下降趋势,腹膜炎发生率有上升趋势。这种趋势部分是由11根导管的反复腹膜炎发作所解释;8.5%的患者经历

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