Satter Elizabeth K
Department of Dermatology and Dermatopathology, Naval Medical Center, San Diego, CA 92134-2300, USA.
Am J Dermatopathol. 2007 Oct;29(5):486-9. doi: 10.1097/DAD.0b013e318156d756.
Although dendritic, melanin-containing melanocytes can be seen in a variety of epithelial neoplasms, only 0.01% to 7% of all squamous cell carcinomas (SCC) are pigmented. Furthermore, most reported cases have occurred in the oral and ocular mucosa, with relatively few cases reported to originate in the skin. Herein we report a case of a 61-year-old Caucasian male who presented with a large blue-black nodule on his left cheek, clinically suspicious for a melanoma; however, histological evaluation revealed an acantholytic pigmented squamous cell carcinoma. Previous cases are reviewed and the clinical and histological differential diagnoses are discussed.
尽管在多种上皮性肿瘤中都能见到呈树枝状、含黑色素的黑素细胞，但在所有鳞状细胞癌（SCC）中，仅有0.01%至7%是色素沉着型的。此外，大多数已报道的病例发生在口腔和眼黏膜，据报道起源于皮肤的病例相对较少。在此，我们报告一例61岁的白种男性病例，该患者左脸颊出现一个大的蓝黑色结节，临床怀疑为黑色素瘤；然而，组织学评估显示为棘层松解性色素沉着型鳞状细胞癌。我们回顾了既往病例，并讨论了临床和组织学鉴别诊断。
