Masuzawa Naoko, Kishimoto Mitsuo, Takahashi Yoshiki
Department of Pathalogy, Otsu Municipal Hospital, Otsu, Japan.
Int J Gynecol Pathol. 2003 Jul;22(3):285-8. doi: 10.1097/01.PGP.0000054824.24312.DE.
A 57-year-old female presented with an abnormal Pap smear. Colposcopic examination of the cervix revealed white mucosa with erosion and several areas of black pigmentation. After a colposcopically directed biopsy and loop conization, radical hysterectomy and bilateral salpingo-oophorectomy with pelvic and paraaortic lymphadenectomy were performed. Pathological examination disclosed an invasive squamous cell carcinoma admixed with many dendritic melanocytes. Melanin granules were present within the melanocytes and tumor cells. Although similar tumors have been reported in other sites, this is the first report to our knowledge of a pigmented squamous cell carcinoma of the uterine cervix.
一名57岁女性因巴氏涂片异常就诊。宫颈阴道镜检查显示白色黏膜伴糜烂及多处黑色色素沉着区。在阴道镜引导下活检及环形电切术后，行根治性子宫切除术、双侧输卵管卵巢切除术及盆腔和腹主动脉旁淋巴结清扫术。病理检查发现为浸润性鳞状细胞癌，混有许多树突状黑素细胞。黑素细胞和肿瘤细胞内均有黑素颗粒。虽然其他部位曾有类似肿瘤的报道，但据我们所知，这是首例关于子宫颈色素沉着性鳞状细胞癌的报告。
