Bourne Robert B, McCalden Richard W, MacDonald Steven J, Mokete Lipalo, Guerin Jeff
London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada.
Clin Orthop Relat Res. 2007 Nov;464:27-31. doi: 10.1097/BLO.0b013e318159c5ff.
Many studies suggest patient factors influence TKA outcomes, but the reported data are controversial, due perhaps in part to using only postoperative scores rather than change in scores from pre- to postoperatively. We examined the effect of gender, age, diagnosis, and obesity on changes in pre- to postoperative outcome measures (Knee Society clinical rating, WOMAC, and SF-12) in a cohort of 843 consecutive knee arthroplasties in 728 patients who received the same implant (Genesis II, Smith & Nephew, Memphis, TN). Minimum followup was 5 years (mean, 9.5 years; range, 5-11 years). Kaplan Meier survivorship was 98% +/- 0.007 with any reoperation as an end point. Male and female patients had similar increases in postoperative scores. Diagnosis and obesity made no difference in postoperative increases. However, less improvement occurred in health-related quality-of-life outcomes scores with advancing age.
许多研究表明患者因素会影响全膝关节置换术（TKA）的结果，但报告的数据存在争议，这可能部分是由于仅使用术后评分，而非术前到术后评分的变化。我们在728例接受相同植入物（Genesis II，史赛克公司，田纳西州孟菲斯）的患者中进行了843例连续膝关节置换术，研究了性别、年龄、诊断和肥胖对术前到术后结果测量指标（膝关节协会临床评分、WOMAC和SF-12）变化的影响。最短随访时间为5年（平均9.5年；范围5 - 11年）。以任何再次手术作为终点，Kaplan Meier生存率为98%±0.007。男性和女性患者术后评分的增加相似。诊断和肥胖对术后增加没有影响。然而，随着年龄增长，与健康相关的生活质量结果评分改善较少。
