Turnover and intranuclear localization of 125I-insulin in Tetrahymena. An autoradiographic study.
作者信息
Fülöp A K, Csaba G
机构信息
Department of Biology, Semmelweis University of Medicine, Budapest, Hungary.
出版信息
Acta Morphol Hung. 1991;39(2):71-7.
PMID:1789147
Abstract
The unicellular Tetrahymena first internalized, then partly released the labelled insulin. Insulin-pretreated (imprinted) Tetrahymena cells behaved differently from non-pretreated cells, in that they retained a greater part of internalized insulin in the cytoplasm. Additional exposure to excessive non-labelled (cold) insulin caused a decrease in intracellular labelled insulin retention. Internalized insulin also entered the nucleus of Tetrahymena, where it was found in a heterochromatic localization.
摘要
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