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[孕期减速的发病机制]

[Pathogenesis of deceleration in the prenatal period].

作者信息

Medvedev M V, Strizhakov A N, Ageeva M I, Kovaleva L G, Savchenko I Iu

出版信息

Akush Ginekol (Mosk). 1991 Dec(12):18-23.

PMID:1789337
Abstract

Comprehensive examination, making use of cardiotocography, dopplerometry, and doppler echocardiography, was carried out to disclose the contribution of fetal hemodynamic disorders to the pathogenesis of antenatal deceleration in 69 pregnant women. Disorders of both intracardiac fetal hemodynamics and of the fetoplacental circulation were revealed in all the cases with deceleration. Therefore, circulatory disorders underlie the pathogenesis of decelerations. The development of decelerations is related to the progressive deterioration of fetoplacental circulation and, specifically, to marked changes in the intracardiac hemodynamics in conditions of augmenting peripheral vascular resistance and hypoxia of the fetus.

摘要

对69名孕妇进行了综合检查,利用胎心宫缩图、多普勒测量法和多普勒超声心动图,以揭示胎儿血流动力学紊乱在产前减速发病机制中的作用。在所有出现减速的病例中均发现了胎儿心内血流动力学和胎儿-胎盘循环的紊乱。因此,循环系统紊乱是减速发病机制的基础。减速的发生与胎儿-胎盘循环的逐渐恶化有关,具体而言,与胎儿外周血管阻力增加和缺氧情况下心内血流动力学的显著变化有关。

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