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地塞米松与氢化可的松治疗小儿重症急性哮喘的疗效比较

Comparative efficacy of dexamethasone versus hydrocortisone in severe acute pediatric asthma.

作者信息

Ebrahimi Sedigheh, Sarkari Bahador

出版信息

Iran J Allergy Asthma Immunol. 2007 Sep;6(3):159-60.

Abstract

This study aimed to compare the efficacy of dexamethasone and hydrocortisone in the treatment of acute paediatric asthma. Forty seven asthmatic children were randomised to receive either dexamethasone (0.6 mg/ml, maximum 16 mg) in a single dose or hydrocortisone (8-10 mg/kg/day) in 4 equal doses for 2 days. Our findings showed that the mean length of hospitalization in children receiving dexamethasone was significantly shorter than those receiving hydrocortisone.

摘要

本研究旨在比较地塞米松和氢化可的松治疗儿童急性哮喘的疗效。47名哮喘儿童被随机分为两组,一组接受单剂量地塞米松(0.6毫克/毫升,最大剂量16毫克),另一组接受氢化可的松(8 - 10毫克/千克/天),分4等份剂量,共治疗2天。我们的研究结果表明,接受地塞米松治疗的儿童平均住院时间明显短于接受氢化可的松治疗的儿童。

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