Korenyi C, Wittman R
Creedmoor Institute for Psychobiologic Studies, Creedmoor State Hospital, Queens Village, NY 11427, USA.
Dis Nerv Syst. 1974 Jan;35(1):17-9.
The prevalence of neuropsychiatric and other medical disorders were determined in offspring from parents with Huntington's Disease (H.D.) and from at risk parents in 254 pedigrees of families with H.D. It was found that the prevalence of such disorders is definitely higher in offspring of parents with the diagnosis of H.D. than in offspring of asymptomatic parents. It is concluded that some polygenic linkage might be responsible for this observation.
在患有亨廷顿舞蹈症（H.D.）的父母的后代以及254个患有H.D.的家族系谱中有患病风险的父母的后代中，确定了神经精神疾病和其他医学疾病的患病率。研究发现，已确诊患有H.D.的父母的后代中此类疾病的患病率肯定高于无症状父母的后代。得出的结论是，某些多基因连锁可能是造成这一观察结果的原因。
