Yoo K M, Shin H K, Chang H M, Caplan L R
Department of Neurology, New England Medical Center, Boston, MA, USA.
J Stroke Cerebrovasc Dis. 1998 Sep-Oct;7(5):344-51. doi: 10.1016/s1052-3057(98)80053-0.
To analyze the clinical features, vascular lesions, and infarct distribution in Asian and white patients with middle cerebral artery (MCA) territory ischemia, we studied age, sex, race, risk factors, angiographic, and neuroimaging findings among patients in the New England Medical Center Stroke Registry. We included patients with well-defined intrinsic occlusive lesions of the MCAs and patients with embolic MCA territory infarcts. Among 695 patients in the stroke registry, 89 (12.8%) qualified. They had 28 MCA intrinsic stenoses, 17 MCA embolic occlusions (cardiogenic or unknown origin), and 44 carotid artery (CA) stenoses or occlusions. MCA intrinsic disease patients were more often Asians and women, and more often had hypertension. Asians were older than whites. Coronary artery disease (27%), peripheral vascular disease (20.5%), and smoking (39%) were more common in CA disease patients. The most common site of MCA intrinsic stenosis (78%) and embolic occlusion (59%) was the mainstem MCA. Infarcts in patients with MCA intrinsic disease mostly involved the striatocapsular area (61%). Infarcts in patients with MCA embolic occlusion (75%) and CA disease (43%) most often involved the parietal lobe. In our hospital, most patients with MCA intrinsic disease are Asians and women and have hypertension and striatocapsular infarctions. Asian patients are usually older than white patients. The most common site of vascular lesions is the mainstem MCA.
为分析亚洲和白人患者大脑中动脉（MCA）区域缺血的临床特征、血管病变及梗死分布情况，我们研究了新英格兰医学中心卒中登记处患者的年龄、性别、种族、危险因素、血管造影及神经影像学检查结果。我们纳入了患有明确的MCA固有闭塞性病变的患者以及患有栓塞性MCA区域梗死的患者。在卒中登记处的695例患者中，89例（12.8%）符合条件。他们有28例MCA固有狭窄、17例MCA栓塞性闭塞（心源或不明来源）以及44例颈动脉（CA）狭窄或闭塞。MCA固有疾病患者中亚洲人和女性更为常见，且高血压更为常见。亚洲人比白人年龄更大。CA疾病患者中冠状动脉疾病（27%）、外周血管疾病（20.5%）及吸烟（39%）更为常见。MCA固有狭窄（78%）和栓塞性闭塞（59%）最常见的部位是MCA主干。MCA固有疾病患者的梗死大多累及纹状囊区（61%）。MCA栓塞性闭塞患者（75%）和CA疾病患者（43%）的梗死最常累及顶叶。在我们医院，大多数患有MCA固有疾病的患者为亚洲人和女性，患有高血压且有纹状囊梗死。亚洲患者通常比白人患者年龄更大。血管病变最常见的部位是MCA主干。
