Papamitsakis N I, Kuyl J, Lutsep H L, Clark W M
Oregon Stroke Center, Oregon Health Sciences University, Portland, Oregon, USA.
J Stroke Cerebrovasc Dis. 2000 Mar-Apr;9(2):79-81. doi: 10.1053/jscd.2000.0090079.
We present a case of acute angioedema after administration of recombinant tissue plasminogen activator (t-PA) for acute ischemic stroke. Our patient was treated with t-PA in accordance with the National Institute of Neurological Disorders and Stroke (NINDS) protocol, and subsequently developed angioedema of the lower lip that subsided within 2 hours. Five patients who required upper airway control after the use of t-PA for ischemic stroke have been reported in the literature. Although the outcome in our case was excellent, development of angioedema after t-PA administration is a potential complication of which treating physicians need to be aware.
我们报告了一例在使用重组组织型纤溶酶原激活剂（t-PA）治疗急性缺血性卒中后发生急性血管性水肿的病例。我们的患者按照美国国立神经疾病和卒中研究所（NINDS）的方案接受了t-PA治疗，随后出现下唇血管性水肿，在2小时内消退。文献中已报道了5例在使用t-PA治疗缺血性卒中后需要进行上呼吸道控制的患者。尽管我们病例的结局良好，但t-PA给药后发生血管性水肿是一种潜在的并发症，治疗医生需要对此有所了解。
