一名患有系统性红斑狼疮的年轻男性的恶性贫血。
Pernicious anemia in a young man with systemic lupus erythematosus.
作者信息
Benjilali L, Tazi-Mezalek Z, Harmouche H, Lebbar K, Aouni M, Adnaoui M, Maaouni A
机构信息
Department of Internal Medicine, Ibn Sina Hospital, Rabat, Morroco.
出版信息
Lupus. 2007;16(10):827-9. doi: 10.1177/0961203307081976.
Association of pernicious anemia and systemic lupus erythematosus is rare, although both diseases are autoimmune origin. We describe the case of a 40-year old man with systemic lupus erythematosus (SLE) who developed pernicious anemia. The cobalamin deficiency was revealed by macrocytic pancytopenia. After 1 month of vitamin B12 treatment, hemoglobin and white blood cell count remain normal but thrombocytopenia persists and was considered as immunologic from SLE origin requiring corticosteroids.
恶性贫血与系统性红斑狼疮的关联较为罕见，尽管这两种疾病均源于自身免疫。我们描述了一名40岁患有系统性红斑狼疮（SLE）的男性患者并发恶性贫血的病例。巨细胞全血细胞减少症揭示了钴胺素缺乏。经过1个月的维生素B12治疗后，血红蛋白和白细胞计数保持正常，但血小板减少症持续存在，且被认为是源自SLE的免疫性血小板减少症，需要使用皮质类固醇治疗。
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