Boucher Bradley A, Hannon Timothy J
Department of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
Pharmacotherapy. 2007 Oct;27(10):1394-411. doi: 10.1592/phco.27.10.1394.
Blood transfusions are common in the hospital setting. Despite the large commitment of resources to the delivery of blood components, many clinicians have only a vague understanding of the complexities associated with blood management and transfusion therapy. The purpose of this primer is to broaden the awareness of health care practitioners in terms of the risks versus benefits of blood transfusions, their economics, and alternative treatments. By developing and implementing comprehensive blood management programs, hospitals can promote safe and clinically effective blood utilization practices. The cornerstones of blood management programs are the implementation of evidence-based transfusion guidelines to reduce variability in transfusion practice, and the employment of multidisciplinary teams to study, implement, and monitor local blood management strategies. Pharmacists can play a key role in blood management programs by providing technical expertise as well as oversight and monitoring of pharmaceutical agents used to reduce the need for allogeneic blood.
输血在医院环境中很常见。尽管在血液成分供应方面投入了大量资源,但许多临床医生对与血液管理和输血治疗相关的复杂性只有模糊的认识。本入门指南的目的是提高医疗从业者对输血的风险与益处、其经济学以及替代治疗方法的认识。通过制定和实施全面的血液管理计划,医院可以促进安全且临床有效的血液使用实践。血液管理计划的基石是实施基于证据的输血指南以减少输血实践中的变异性,以及组建多学科团队来研究、实施和监测当地的血液管理策略。药剂师可以在血液管理计划中发挥关键作用,提供专业技术知识以及对用于减少异体输血需求的药物进行监督和监测。