Liu S M, Liu W M
Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, UK.
Protein Pept Lett. 2007;14(7):723-33. doi: 10.2174/092986607781483895.
The process of nucleocytoplasmic exchange of various macromolecules and metabolites between the nuclear and cytoplasmic compartment is crucial for cell function and survival. It is also closely involved with several pathogeneses including cancer and viral infections. Here, we will discuss the current understanding of the classical nuclear import pathway and the factors that are essential for this process.
细胞核与细胞质区室之间各种大分子和代谢物的核质交换过程对于细胞功能和存活至关重要。它还与包括癌症和病毒感染在内的几种发病机制密切相关。在这里，我们将讨论对经典核输入途径的当前理解以及该过程所必需的因素。
