Krishnasamy Rajkumar, Agarwal Shaleen, Singh Shivendra, Puri Sunil, Sakhuja Puja, Agarwal Anil K
Department of Gastrointestinal Surgery, Govind Ballabh Pant Hospital and Maulana Azad Medical College (Delhi University), New Delhi 110002, India.
Hepatobiliary Pancreat Dis Int. 2007 Oct;6(5):553-6.
The presence of pancreatic ductal intraepithelial neoplasia in patients with chronic pancreatitis is a risk factor for development of pancreatic adenocarcinoma.
A case of pancreatic ductal adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia was diagnosed in the setting of chronic pancreatitis.
Distal pancreatectomy combined with splenectomy was performed with a diagnosis of pancreatic body carcinoma. Histopathological examination suggested adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia. The tumor was detected in the remaining head of the pancreas, for which a total pancreatectomy was done.
When a patient with pancreatic ductal intraepithelial neoplasia associated with adenocarcinoma of the pancreas in the setting of chronic pancreatitis is at an increased risk of recurrence in the remaining pancreatic parenchyma, total pancreatectomy may be feasible.
慢性胰腺炎患者存在胰腺导管上皮内瘤变是发生胰腺腺癌的危险因素。
在慢性胰腺炎背景下诊断出一例与胰腺导管上皮内瘤变相关的胰腺导管腺癌病例。
诊断为胰体癌后行远端胰腺切除术联合脾切除术。组织病理学检查提示为与胰腺导管上皮内瘤变相关的腺癌。在剩余的胰头发现肿瘤，为此进行了全胰切除术。
当慢性胰腺炎背景下伴有胰腺腺癌的胰腺导管上皮内瘤变患者剩余胰腺实质复发风险增加时，全胰切除术可能是可行的。
