Seider M J, Cleary K R, van Tassel P, Alexanian R, Schantz S P, Frias A, Fuller L M
Department of Clinical Radiotherapy, University of Texas M. D. Anderson Cancer Center, Houston 77030.
Cancer. 1991 Feb 15;67(4):929-32. doi: 10.1002/1097-0142(19910215)67:4<929::aid-cncr2820670412>3.0.co;2-q.
Plasma cell granuloma is a rare, benign tumor most commonly found in the lungs in patients younger than 30 years. Although presentation has been reported at a number of other anatomic sites, this report is the first of plasma cell granuloma of the nasal cavity. The tumor was initially resected, but progression was seen at 1-month follow-up. Because further surgery to completely eradicate the tumor would have been extensive and disfiguring, 40-Gy external beam radiation was given in 20 fractions using a three-field wedge technique. Most recent clinical follow-up at 27 months showed local control. Surgery remains the treatment of choice for plasma cell granuloma when the disease can be completely resected. However, irradiation can also be effective in patients with recurrent or inoperable local disease.
浆细胞性肉芽肿是一种罕见的良性肿瘤，最常见于30岁以下患者的肺部。虽然已有报道称该肿瘤可出现在其他一些解剖部位，但本报告是鼻腔浆细胞性肉芽肿的首例报道。该肿瘤最初进行了切除，但在1个月的随访中出现了进展。由于进一步手术以彻底根除肿瘤会范围广泛且导致容貌受损，因此采用三野楔形技术分20次给予40 Gy的外照射。27个月的最新临床随访显示肿瘤得到了局部控制。当疾病能够完全切除时，手术仍然是浆细胞性肉芽肿的首选治疗方法。然而，对于局部复发或无法手术的患者，放疗也可能有效。
