Rosen Daniel J, Patel Mitesh K, Freeman Katherine, Weiss Paul R
Bronx and New York, N.Y. From the Department of Plastic and Reconstructive Surgery, Montefiore Medical Center-Albert Einstein College of Medicine, and the Department of General Surgery, St. Lukes-Roosevelt Hospital Center.
Plast Reconstr Surg. 2007 Oct;120(5):1395-1400. doi: 10.1097/01.prs.0000279373.25099.2a.
Keloids of the ear are a challenging problem, with many treatment modalities advocated. The primary determinant in choosing a treatment protocol should be a low recurrence rate. Most reports in the literature suffer from small numbers of patients and inadequate follow-up.
This study presents a retrospective analysis of 64 patients representing 92 ear keloids treated between 1982 and 1997. The treatment protocol consisted of excision with an intraoperative and two postoperative steroid injections. All patients were treated by a single physician. Long-term follow-up was obtained at a minimum of 5 years.
Protocol success was achieved in 74 of 92 keloids (80 percent) excised. Prior excision of the keloid was significantly associated with protocol failure (p = 0.0068). Keloid recurrence was seen in 10 of 43 (23 percent). Statistically significant differences were noted in keloids that had undergone prior excision as compared with those presenting for initial treatment. These differences included growth rate (p = 0.0026), protocol failure (p = 0.0149), and total postoperative steroid injections administered (p = 0.0104).
The primary protocol presented for the treatment of ear keloids produces durable results, with an acceptably low recurrence rate. Stratification of keloids based on an assessment of aggressiveness may allow for a more informed choice in their optimal treatment.
耳部瘢痕疙瘩是一个具有挑战性的问题,有多种治疗方法被提倡。选择治疗方案的主要决定因素应该是低复发率。文献中的大多数报告患者数量较少且随访不足。
本研究对1982年至1997年间治疗的64例患者的92个耳部瘢痕疙瘩进行了回顾性分析。治疗方案包括手术切除并在术中及术后进行两次类固醇注射。所有患者均由一名医生治疗。至少进行了5年的长期随访。
92个切除的瘢痕疙瘩中有74个(80%)治疗成功。瘢痕疙瘩先前切除与治疗失败显著相关(p = 0.0068)。43个中有10个(23%)出现瘢痕疙瘩复发。与初次治疗的瘢痕疙瘩相比,先前切除的瘢痕疙瘩在统计学上有显著差异。这些差异包括生长速度(p = 0.0026)、治疗失败(p = 0.0149)和术后类固醇注射总量(p = 0.0104)。
所提出的耳部瘢痕疙瘩主要治疗方案产生了持久的效果,复发率低至可接受。根据侵袭性评估对瘢痕疙瘩进行分层可能有助于在其最佳治疗中做出更明智的选择。