Fontaine Bertrand, Peremans Herbert
Biol Cybern. 2007 Oct;97(4):261-7. doi: 10.1007/s00422-007-0178-9.
Bats, like other mammals, are known to use interaural intensity differences (IID) to determine azimuthal position. In the lateral superior olive (LSO) neurons have firing behaviors which vary systematically with IID. Those neurons receive excitatory inputs from the ipsilateral ear and inhibitory inputs from the contralateral one. The IID sensitivity of a LSO neuron is thought to be due to delay differences between the signals coming from both ears, differences due to different synaptic delays and to intensity-dependent delays. In this paper we model the auditory pathway until the LSO. We propose a learning scheme where inputs to LSO neurons start out numerous with different relative delays. Spike timing-dependent plasticity (STDP) is then used to prune those connections. We compare the pruned neuron responses with physiological data and analyse the relationship between IID's of teacher stimuli and IID sensitivities of trained LSO neurons.
与其他哺乳动物一样，蝙蝠已知会利用双耳强度差（IID）来确定方位位置。在外侧上橄榄核（LSO）中，神经元具有随IID系统性变化的放电行为。这些神经元从同侧耳朵接收兴奋性输入，从对侧耳朵接收抑制性输入。LSO神经元的IID敏感性被认为是由于来自双耳的信号之间的延迟差异，这种差异是由不同的突触延迟和强度依赖性延迟造成的。在本文中，我们对直到LSO的听觉通路进行建模。我们提出一种学习方案，其中LSO神经元的输入最初数量众多且具有不同的相对延迟。然后使用依赖于尖峰时间的可塑性（STDP）来修剪这些连接。我们将修剪后的神经元反应与生理数据进行比较，并分析教师刺激的IID与训练后的LSO神经元的IID敏感性之间的关系。
