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[肉毒杆菌毒素治疗后脑瘫患者手部功能障碍的患病率]

[Prevalence of hand dysfunction in cerebral palsy following Botulinum toxin therapy].

作者信息

Alahmar-Bianchin M, Saraiva-Storti H C, Fornari-Chueri R, Lucato R V

机构信息

Facultad de Medicina, São Jose do Rio Preto, São Paulo, Brasil.

出版信息

Rev Neurol. 2007;45(6):334-7.

Abstract

AIM

To examine the level of dependence, the functional class, the most frequent type of compromise and the proprioception of the hand in spastic cerebral palsy following the application of botulinum toxin, as well as to determine the sociodemographic characteristics of the individuals involved.

PATIENTS AND METHODS

We conducted a cross-sectional study of 21 spastic patients with extrinsic muscle involvement, of both sexes and a mean age of 15.4 +/- 5.6 years, who attended the neuro-rehabilitation outpatients department and were treated with botulinum toxin in the muscles responsible for the functional movements in the hand; they were evaluated after a mean period of 2.1 years. Patients were subjected to procedures such as a semi-structured interview, the FIM (Functional Independence Measurement) scale, Hausen's functional characterisation, Zancolli classification and a proprioception test.

RESULTS

There was a predominance of females (57% of patients) and of a basic level of schooling. On the FIM scale, 38% of the patients presented modified independence, without help; 23.8% belonged to Hausen grade 3 (grasping and holding an object steady with the help of the other hand). On the Zancolli classification, 54% belonged to type III (the fingers can only be extended if the fist is bent more than 70 masculine); perception of movement is absent (76.2%) and the sense of position of the movement is altered (54.2%).

CONCLUSIONS

Findings confirmed the existence of a high rate of modified independence, grade 3 (Hausen), together with type III involvement (Zancolli) and alterations affecting proprioception. Data from the study show the importance of occupational therapy as part of the care received by patients with cerebral palsy following the administration of botulinum toxin type A.

摘要

目的

研究肉毒杆菌毒素应用后痉挛性脑瘫患者手部的依赖程度、功能分级、最常见的功能受限类型和本体感觉,以及确定所涉及个体的社会人口学特征。

患者与方法

我们对21例有手部外在肌肉受累的痉挛性患者进行了横断面研究,患者性别不限,平均年龄为15.4±5.6岁,他们在神经康复门诊就诊,并在手功能运动相关肌肉接受肉毒杆菌毒素治疗;平均2.1年后对他们进行评估。患者接受了半结构化访谈、FIM(功能独立性测量)量表、豪森功能特征评估、赞科利分类和本体感觉测试等检查。

结果

女性占多数(占患者的57%),且受教育程度为基础水平。在FIM量表上,38%的患者表现为有条件独立,无需帮助;23.8%属于豪森3级(借助另一只手抓握并稳定握住物体)。在赞科利分类中,54%属于Ⅲ型(只有当拳头弯曲超过70度时手指才能伸展);运动感知缺失(76.2%),运动位置觉改变(54.2%)。

结论

研究结果证实存在较高比例的有条件独立、3级(豪森),以及Ⅲ型受累(赞科利)和影响本体感觉的改变。研究数据表明,职业治疗作为A型肉毒杆菌毒素治疗后脑瘫患者所接受护理的一部分具有重要意义。

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