Qin Yingjie, Yu Xixun, Chen Yuanwei, Ding Yulong, Wan Changxiu
Department of Polymer Materials and Engineering, Sichuan University, Chengdu 610065, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2007 Aug;24(4):794-7.
This study was undertaken to elucidate the degradation regularity of calcium polyphosphate (CPP) scaffolds with different preparation parameters. CPP scaffolds with different main crystalline phases were prepared by controlling the particle size of the calcining stuff and the calcining heat. Specimens were soaked into Tris-buffer solution and simulated body fluid (SBF) for 60 days. Results show: alpha-CPP degrades faster than does beta-CPP, and beta-CPP degrades faster than does gamma-CPP; the lower the sinter temperature, the better the degradation of CPP morever, the degradation rate of CPP is inversely proportional to the original particle size. These data suggest that crystal type, sinter temperature and particle size influence the degradation rate of CPP markedly.
本研究旨在阐明具有不同制备参数的聚磷酸钙（CPP）支架的降解规律。通过控制煅烧原料的粒径和煅烧温度，制备了具有不同主要晶相的CPP支架。将试样浸泡在Tris缓冲溶液和模拟体液（SBF）中60天。结果表明：α-CPP比β-CPP降解更快，β-CPP比γ-CPP降解更快；烧结温度越低，CPP的降解性能越好，而且CPP的降解速率与原始粒径成反比。这些数据表明，晶体类型、烧结温度和粒径对CPP的降解速率有显著影响。
