通过对韩国人群进行测序鉴定新型HLA-G亚型HLA-G*0109。

Identification of novel HLA-G subtype, HLA-G*0109, by sequencing in the Korean population.

作者信息

Kang H, Yun H-S, Song M-Y, Lee J-K, Kwack K

机构信息

Medical Genomics Laboratory, CHA Research Institute, Pochon CHA University, Sungnam, Korea.

出版信息

Tissue Antigens. 2007 Dec;70(6):529-30. doi: 10.1111/j.1399-0039.2007.00933.x. Epub 2007 Sep 27.

DOI:10.1111/j.1399-0039.2007.00933.x

PMID:17900287

Abstract

We identified the novel human leukocyte antigen-G*0109 allele in the Korean population by direct sequencing. This allele has a single-nucleotide substitution at nucleotide residue 547 in codon 159 that results in an amino acid change from tyrosine to histidine.

摘要

我们通过直接测序在韩国人群中鉴定出了新型人类白细胞抗原-G*0109 等位基因。该等位基因在第159密码子的核苷酸残基547处发生单核苷酸替换，导致氨基酸由酪氨酸变为组氨酸。