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内镜检查在十二指肠憩室出血管理中的作用:单中心经验及近期文献综述

Impact of endoscopy in the management of duodenal diverticular bleeding: experience of a single medical center and a review of recent literature.

作者信息

Chen Yang-Yuan, Yen Hsu-Heng, Soon Maw-Soan

机构信息

Department of Gastroenterology, Changhua Christian Medical Center, Changhua, Taiwan.

出版信息

Gastrointest Endosc. 2007 Oct;66(4):831-5. doi: 10.1016/j.gie.2007.06.001.

Abstract

BACKGROUND

Duodenal diverticulum (DD) is a rare cause of upper-GI bleeding. The diagnosis and treatment of DD bleeding (DDB) is challenging. Surgical management was the mainstay of therapy before the 1990s.

OBJECTIVE

To evaluate the clinical feature, diagnosis, and management of cases of DDB at our institution and the literature after the first description of endoscopic therapy of this disease.

DESIGN

Retrospective single-center clinical review.

SETTING

Primary- and tertiary-care centers.

PATIENTS

A retrospective study of patients with DDB from January 2000 to January 2005 at Changhua Christian Medical Center.

MAIN OUTCOME MEASUREMENTS

Diagnostic yield and therapy results of endoscopy on DDB.

RESULTS

At our institution, from January 2000 to January 2005, a total of 11 patients (4 men and 7 women, mean age 75 years) were found to have DDB. The diverticulum was located in the second portion (n = 10) and the third portion (n = 1). Endoscopy was used as the diagnostic method in all of these cases and as the therapeutic method in 72.73% of these cases. None of our patients experienced recurrent bleeding.

LIMITATIONS

The study is limited to the small case number and was retrospective.

CONCLUSIONS

To our knowledge, this is the first report and the largest series that studied endoscopic management of DDB in the literature. We concluded that endoscopy is useful to diagnose and treat patients with DDB.

摘要

背景

十二指肠憩室(DD)是上消化道出血的罕见病因。十二指肠憩室出血(DDB)的诊断和治疗具有挑战性。在20世纪90年代之前,手术治疗是主要的治疗方法。

目的

评估我院DDB病例的临床特征、诊断和治疗情况,以及自该疾病内镜治疗首次被描述以来的文献情况。

设计

回顾性单中心临床研究。

地点

一级和三级医疗中心。

患者

对2000年1月至2005年1月在彰化基督教医疗中心诊断为DDB的患者进行回顾性研究。

主要观察指标

内镜检查对DDB的诊断率和治疗效果。

结果

在我院,2000年1月至2005年1月期间,共发现11例DDB患者(4例男性,7例女性,平均年龄75岁)。憩室位于十二指肠第二部(n = 10)和第三部(n = 1)。所有这些病例均采用内镜检查作为诊断方法,72.73%的病例采用内镜检查作为治疗方法。我们的患者均未出现复发性出血。

局限性

本研究限于病例数量少且为回顾性研究。

结论

据我们所知,这是文献中关于DDB内镜治疗的首例报告及最大系列研究。我们得出结论,内镜检查对DDB患者的诊断和治疗有用。

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