Onozato Yasuhiro, Kakizaki Satoru, Ishihara Hiroshi, Iizuka Haruhisa, Sohara Naondo, Okamura Shinichi, Mori Masatomo, Itoh Hideaki
Center of Gastroenterology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan.
Gastrointest Endosc. 2007 Nov;66(5):1042-9. doi: 10.1016/j.gie.2007.07.014.
Although the presence of a duodenal diverticulum is usually asymptomatic, bleeding in this tissue is sometimes difficult to diagnose and treat.
To investigate the strategy for treatment, we reviewed the clinical data of patients diagnosed and treated for duodenal diverticular bleeding.
Retrospective case series.
Single tertiary-referral center.
Seven consecutive patients with bleeding from a duodenal diverticulum (mean age, 73.7 +/- 3.4 years old).
The clinical characteristics, endoscopic findings, and treatment strategy for duodenal diverticular bleeding.
All 7 patients achieved hemostasis. Six of 7 patients were treated endoscopically. There were no complications with endoscopic treatment.
Three patients bled from diverticula located at the second portion of the duodenum, and 4 patients bled from that located at the third portion. In 6 of 7 patients, lesions were identified and treated endoscopically with hemoclips, hypertonic saline solution and epinephrine (HSE), and/or 1% polidocanol injection. In 1 case, the lesion could not be detected during the first endoscopic examination, and the patient, therefore, was treated with transarterial embolization followed by surgical resection.
This preliminary case series described the feasibility of the endoscopic treatment. However, optimal management, including angiography and/or surgery, should be individualized to the patients, location, and type of hemorrhage.
Bleeding from a duodenal diverticulum should be considered in the case of upper-GI bleeding of unknown origin. An endoscopy may be an effective alternative to surgery in the management of a bleeding duodenal diverticulum.
尽管十二指肠憩室通常无症状,但该组织出血有时难以诊断和治疗。
为了研究治疗策略,我们回顾了诊断和治疗十二指肠憩室出血患者的临床资料。
回顾性病例系列研究。
单一的三级转诊中心。
7例连续的十二指肠憩室出血患者(平均年龄73.7±3.4岁)。
十二指肠憩室出血的临床特征、内镜检查结果及治疗策略。
所有7例患者均实现止血。7例患者中有6例接受了内镜治疗。内镜治疗无并发症发生。
3例患者的憩室位于十二指肠第二部,4例患者的憩室位于十二指肠第三部。7例患者中有6例通过内镜用止血夹、高渗盐水溶液和肾上腺素(HSE)及/或1%聚多卡醇注射进行病变识别和治疗。1例患者在首次内镜检查时未发现病变,因此先接受经动脉栓塞治疗,随后接受手术切除。
这个初步病例系列描述了内镜治疗的可行性。然而,包括血管造影和/或手术在内的最佳治疗方案应根据患者、出血部位和出血类型进行个体化选择。
不明原因的上消化道出血应考虑十二指肠憩室出血。在内镜治疗十二指肠憩室出血方面,内镜检查可能是手术的有效替代方法。