Borgia M C, De Paola G, Di Folco G, Calpicchio A
Clinica Medica II, Università degli Studi La Sapienza, Roma.
Cardiologia. 1991 Jul;36(7):577-80.
Nifedipine-induced gingival hypertrophy is a rare side effect reported by the producers of this drug but, surely, not well known in all its aspects. In the present case report this pathology is studied in a patient treated with nifedipine for 30 months for cardiac angina, analyzing the histologic features, the therapy plain conducted for the hypertrophy and the most important pathogenetic theories formulated till now.
硝苯地平引起的牙龈肥大是该药物生产商报告的一种罕见副作用,但肯定并非其所有方面都广为人知。在本病例报告中,对一名因心绞痛接受硝苯地平治疗30个月的患者的这种病理情况进行了研究,分析了组织学特征、针对肥大采取的治疗方案以及迄今为止提出的最重要的发病机制理论。