Busch V J J F, Gardeniers J W M, Slooff T J J H, Veth R P H, Schreurs B W
Universitair Medisch Centrum St. Radboud, afd. Orthopedie 800, Postbus 9101, 6500 HB, Nijmegen.
Ned Tijdschr Geneeskd. 2007 Sep 1;151(35):1935-40.
Determination of long-term results of hip replacements in patients who, at the time of operation, were under the age of 50. Procedures whereby an existing acetabulum defect was filled with bone chips that were impacted into a strong layer, after which a cemented total hip prosthesis was implanted.
Descriptive.
Prospectively collected data from patients who were under the age of 50, and had undergone a hip replacement operation at our hospital between 1 July 1979 and 31 December 1987 were analysed. Data were collected up to 31 December 2002. The main outcome was time to revision. Survival was calculated by the Kaplan-Meier method.
The study group consisted of 25 patients, 17 women and 8 men with 29 prosthetic hips. The average age at operation was 37.6 years (range: 20-49). Follow-up time was 15-23 years (median: 18.7 years). 1 patient (1 hip) was lost to follow-up. 3 patients (4 hips) died within 15 years after the operation; none of them had undergone revision. 4 revisions had been performed: I septic loosening (14 years p.o.) and 3 aseptic loosenings (6, 15, 20 years p.o.). The cumulative survival with the end-point 'revision for any reason' was 96% (95% CI: 88-100) at to years and 88% (95% CI: 74-100) at 20 years; after exclusion of the septic loosening the survival at 20 years was 92% (95% CI: 80-100).
Hip replacement including a reconstruction technique for an acetabulum defect in patients under the age of 50 was regarded as successful if after 10 years, at least 90% of the prostheses were still in situ.
确定手术时年龄在50岁以下的患者髋关节置换的长期结果。采用的手术方法是用骨块填充现有的髋臼缺损并将其压入坚固层,之后植入骨水泥型全髋关节假体。
描述性研究。
对前瞻性收集的1979年7月1日至1987年12月31日期间在我院接受髋关节置换手术、年龄在50岁以下患者的数据进行分析。数据收集至2002年12月31日。主要结局指标为翻修时间。采用Kaplan-Meier法计算生存率。
研究组由25例患者组成,其中女性17例,男性8例,共29个假体髋关节。手术时的平均年龄为37.6岁(范围:20 - 49岁)。随访时间为15 - 23年(中位数:18.7年)。1例患者(1个髋关节)失访。3例患者(4个髋关节)在术后15年内死亡;均未进行翻修。已进行了4次翻修:1例为感染性松动(术后14年),3例为无菌性松动(术后6、15、20年)。以“因任何原因进行翻修”为终点的累积生存率在10年时为96%(95%可信区间:88 - 100),在20年时为88%(95%可信区间:74 - 100);排除感染性松动后,20年时的生存率为92%(95%可信区间:80 - 100)。
对于50岁以下患者的髋关节置换,包括髋臼缺损重建技术,如果10年后至少90%的假体仍在位,则认为手术成功。