Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, Southmead Hospital, Bristol, UK.
Health and Policy Research Group, University of Exeter, Exeter, UK.
Lancet. 2019 Feb 16;393(10172):647-654. doi: 10.1016/S0140-6736(18)31665-9. Epub 2019 Feb 14.
Total hip replacement is a common and highly effective operation. All hip replacements would eventually fail if in situ long enough and it is important that patients understand when this might happen. We aimed to answer the question: how long does a hip replacement last?
We did a systematic review and meta-analysis with a search of MEDLINE and Embase from the start of records to Sept 12, 2017. We included articles reporting 15-year survival of primary, conventional total hip replacement constructs in patients with osteoarthritis. We extracted survival and implant data and used all-cause construct survival as the primary outcome. We also reviewed reports of national joint replacement registries, and extracted data for a separate analysis. In the meta-analyses, we weighted each series and calculated a pooled survival estimate for each source of data. This study was registered with PROSPERO (CRD42018085642).
We identified 140 eligible articles reporting 150 series, and included 44 of these series (13 212 total hip placements). National joint replacement registries from Australia and Finland provided data for 92 series (215 676 total hip replacements). The 25-year pooled survival of hip replacements from case series was 77·6% (95% CI 76·0-79·2) and from joint replacement registries was 57·9% (95% CI 57·1-58·7).
Assuming that estimates from national registries are less likely to be biased, patients and surgeons can expect a hip replacement to last 25 years in around 58% of patients.
National Institute for Health Research, National Joint Registry for England, Wales, Northern Ireland and Isle of Man, and The Royal College of Surgeons of England.
全髋关节置换术是一种常见且非常有效的手术。如果所有髋关节置换术的假体在原位时间足够长,那么所有髋关节置换术最终都会失败,而重要的是患者需要了解何时可能发生这种情况。我们旨在回答以下问题:髋关节置换术的使用寿命有多长?
我们进行了一项系统综述和荟萃分析,检索了 MEDLINE 和 Embase 从记录开始到 2017 年 9 月 12 日的数据。我们纳入了报告原发性、常规全髋关节置换术在骨关节炎患者中 15 年生存率的文章。我们提取了生存和植入物数据,并将全因假体生存率作为主要结局。我们还回顾了国家关节置换登记处的报告,并提取了单独分析的数据。在荟萃分析中,我们对每个系列进行加权,并为每个数据源计算汇总生存率估计。本研究已在 PROSPERO(CRD42018085642)上注册。
我们确定了 140 篇符合条件的文章,报道了 150 个系列,其中包括 44 个系列(13212 个全髋关节置换术)。来自澳大利亚和芬兰的国家关节置换登记处提供了 92 个系列(215676 个全髋关节置换术)的数据。病例系列中髋关节置换术的 25 年汇总生存率为 77.6%(95%CI 76.0-79.2),而来自关节置换登记处的生存率为 57.9%(95%CI 57.1-58.7)。
假设国家登记处的估计值不太可能存在偏差,那么在大约 58%的患者中,患者和外科医生可以预期髋关节置换术的使用寿命为 25 年。
英国国家卫生研究院、英格兰、威尔士、北爱尔兰和马恩岛国家关节登记处以及英国皇家外科医师学院。