Holte Espen, Vegsundvåg Johnny, Wiseth Rune
Department of Internal Medicine, Alesund Hospital, Alesund, Norway.
Cardiovasc Ultrasound. 2007 Oct 1;5:33. doi: 10.1186/1476-7120-5-33.
Non-invasive imaging of coronary arteries by transthoracic echocardiography is an emerging diagnostic tool to study the left main (LM), left descending artery (LAD), circumflex (Cx) and right coronary artery (RCA). Impaired coronary circulation can be assessed by measuring coronary velocity flow reserve (CVFR) by transthoracic Doppler echocardiography. Coronary artery stenoses can be identified as localized colour aliasing and accelerated flow velocities. We report a case with an acute coronary syndrome (ACS) of a 46-year-old man. With non-invasive imaging of coronary arteries by transthoracic echocardiography (TTE), we identified a segment of the mid right coronary artery (RCA) suggestive of stenosis with localized colour aliasing and accelerated flow velocity. We found a high ratio between the stenotic peak velocity and the prestenotic peak velocity, and a pathologic coronary flow velocity reserve (CFVR) distal to the stenosis in the posterior interventricular descending branch (RDP). Subsequent coronary angiography demonstrated one vessel disease with a stenosis in segment 3 of RCA, which was successfully treated with percutaneos coronary intervention PCI. Two weeks following the PCI procedure he was readmitted to hospital with chest pain. A subacute stent thrombosis was questioned, and repeated echocardiography was preformed. The mid portion of RCA showed normal and laminar flow. The CVFR of RCA measured in the RDP showed normal vasodilatory response, confirming an open RCA without any flow limitation. A repeated coronary angiogram demonstrated only a mild in stent intimal hyperplasia. This case illustrates the value of transthoracic echocardiography as a tool both in the diagnosis and the follow-up of chest pain disorders and coronary flow problems. Transthoracic echocardiography allows both direct visualization of the various coronary segments and assessment of the CVFR.
经胸超声心动图对冠状动脉进行无创成像,是一种用于研究左主干(LM)、左前降支(LAD)、回旋支(Cx)和右冠状动脉(RCA)的新兴诊断工具。经胸多普勒超声心动图通过测量冠状动脉血流储备(CVFR),可评估冠状动脉循环受损情况。冠状动脉狭窄可表现为局部彩色血流信号混叠和血流速度加快。我们报告一例46岁男性急性冠状动脉综合征(ACS)病例。通过经胸超声心动图(TTE)对冠状动脉进行无创成像,我们发现右冠状动脉(RCA)中段有一段区域存在狭窄迹象,表现为局部彩色血流信号混叠和血流速度加快。我们发现狭窄处峰值速度与狭窄前峰值速度之比很高,且在室间后降支(RDP)狭窄远端存在病理性冠状动脉血流速度储备(CFVR)。随后的冠状动脉造影显示单支血管病变,RCA第3段存在狭窄,经皮冠状动脉介入治疗(PCI)成功治疗。PCI术后两周,他因胸痛再次入院。怀疑发生亚急性支架血栓形成,遂再次进行超声心动图检查。RCA中段血流显示正常且呈层流。在RDP测量的RCA的CVFR显示血管舒张反应正常,证实RCA通畅且无任何血流限制。再次冠状动脉造影仅显示支架内轻度内膜增生。该病例说明了经胸超声心动图作为胸痛疾病和冠状动脉血流问题诊断及随访工具的价值。经胸超声心动图既能直接观察冠状动脉各段情况,又能评估CVFR。