Lassalle Sandra, Butori Catherine, Hofman Véronique, Gari-Toussaint Martine, Mouroux Jérôme, Hofman Paul
Laboratoire de Pathologie Clinique et Expérimentale, Hôpital Pasteur, BP 69, 06002 Nice Cedex.
Ann Pathol. 2007 Apr;27(2):141-4. doi: 10.1016/s0242-6498(07)91302-4.
Pulmonary mucormycosis occur in immunosuppressed patients with a neutropenic treatment or a malignant neoplasia. Although the histological study alone cannot enable species identification, the pathologist usually makes the diagnosis of mucormycosis and can eliminate other filamentous mycoses such as aspergillosis or scedosporiosis. Pulmonary infection caused by Cunninghamella bertholletiae is a very rare lung mucormycosis, particularly in young patients. The histological features of this filamentous mycosis are unusual making the diagnosis of mucormycosis difficult. Mycological study is then crucial for the diagnosis. We report a case of a pulmonary infection caused by Cunninghamella bertholletiae occurring in a young girl with acute lymphoblastic leukemia.
肺毛霉病发生于接受中性粒细胞减少治疗或患有恶性肿瘤的免疫抑制患者。虽然仅靠组织学研究无法进行菌种鉴定,但病理学家通常能做出毛霉病的诊断,并可排除其他丝状真菌病,如曲霉病或赛多孢菌病。由柏氏小克银汉霉引起的肺部感染是一种非常罕见的肺毛霉病,尤其在年轻患者中。这种丝状真菌病的组织学特征不寻常,使得毛霉病的诊断困难。因此,真菌学研究对诊断至关重要。我们报告一例由柏氏小克银汉霉引起的肺部感染病例,该病例发生在一名患有急性淋巴细胞白血病的年轻女孩身上。