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免疫吸附疗法在自身免疫性大疱性疾病治疗中的应用建议。

Recommendations for the use of immunoapheresis in the treatment of autoimmune bullous diseases.

作者信息

Zillikens Detlef, Derfler Kurt, Eming Rüdiger, Fierlbeck Gerhard, Goebeler Matthias, Hertl Michael, Hofmann Silke C, Karlhofer Franz, Kautz Ocko, Nitschke Martin, Opitz Andreas, Quist Sven, Rose Christian, Schanz Stefan, Schmidt Enno, Shimanovich Iakov, Michael Michael, Ziller Fabian

机构信息

Department of Dermatology, University of Lübeck, Germany.

出版信息

J Dtsch Dermatol Ges. 2007 Oct;5(10):881-7. doi: 10.1111/j.1610-0387.2007.06342.x.

Abstract

Despite the use of high-dose systemic corticosteroids in combination with other immunosuppressants, in some patients with autoimmune bullous diseases only insufficient improvement is achieved. In these cases and in acute severe disease, adjuvant immunoapheresis has been increasingly used. A consensus meeting was held in mid-2005 in Hamburg, aiming at developing guidelines for the use of immunoapheresis in the treatment of autoimmune bullous diseases. This paper summarizes the experts' recommendations.

摘要

尽管使用了高剂量全身性皮质类固醇联合其他免疫抑制剂,但在一些自身免疫性大疱性疾病患者中,仅取得了不充分的改善。在这些情况下以及急性重症疾病中,辅助性免疫吸附疗法的使用越来越多。2005年年中在汉堡召开了一次共识会议,旨在制定免疫吸附疗法用于治疗自身免疫性大疱性疾病的指南。本文总结了专家的建议。

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