O'Connor A R, Wilson C M, Fielder A R
Division of Orthoptics, University of Liverpool, Liverpool, UK.
Eye (Lond). 2007 Oct;21(10):1254-60. doi: 10.1038/sj.eye.6702838.
As survival of preterm infants improves, the long-term care of consequent ophthalmic problems is an expanding field. Preterm birth can inflict a host of challenges on the developing ocular system, resulting in the visual manifestations of varied significance and pathological scope. The ophthalmic condition most commonly associated with preterm birth is retinopathy of prematurity, which has the potential to result in devastating vision loss. However, the visual compromise from increased incidence of refractive errors, strabismus, and cerebral vision impairment has significant impact on visual function, which also has influence on other developmental aspects including psychological and educational. In this review, the normal ocular development is discussed, aiming to exemplify the impact of early exteriorisation on one of the more naive organs of prematurity. This is then related to the incidence and visual consequences of many types of deficit, including refractive error, strabismus, and loss of visual function in preterm populations, with comparisons to term infant studies. Often these conditions are linked with causal and resultant factors being impossible to segregate, but the common factor of increased rates of all types of ophthalmic deficits demonstrates that children born prematurely are indeed premature for life.
随着早产儿存活率的提高,随之而来的眼部问题的长期护理成为一个不断扩大的领域。早产会给发育中的眼部系统带来诸多挑战,导致具有不同程度重要性和病理范围的视觉表现。与早产最常见相关的眼部疾病是早产儿视网膜病变,它有可能导致严重的视力丧失。然而,屈光不正、斜视和脑性视力损害发病率增加所导致的视力受损对视觉功能有重大影响,这也会影响包括心理和教育在内的其他发育方面。在本综述中,将讨论正常的眼部发育,旨在举例说明早期宫外生活对早产儿较稚嫩器官之一的影响。然后将其与早产人群中多种缺陷的发生率和视觉后果相关联,包括屈光不正、斜视和视觉功能丧失,并与足月儿研究进行比较。通常这些情况的因果因素难以区分,但所有类型眼部缺陷发生率增加这一共同因素表明,早产出生的儿童在生活中确实处于“早产”状态。