Lin Hsu-Ying, Wu Wei-Chi, Sun Ming-Hui, Lin Jui-Yen, Huang Ping-Hsuan, Liu Chun-Hsiu
Department of Ophthalmology, Chang Gung Memorial Hospital, Keelung, Taiwan.
Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.
J Ophthalmol. 2024 Dec 19;2024:6982201. doi: 10.1155/joph/6982201. eCollection 2024.
This study aimed to compare ocular torsion measurements to investigate normative objective cyclotorsion values in a population of healthy, full-term and preterm children. The participants enrolled in this study had an age range of 3-12 years and were divided into two groups, full-term (gestational age (GA) > 37 weeks) and preterm without retinopathy of prematurity (ROP) (GA ≤ 37 weeks). The disc-center-fovea angle (DFA) was used to evaluate ocular torsion using two different imaging modalities: optical coherence tomography (OCT) with a 55-degree field of view (FV) and conventional fundus photography (CFP) with a 45-degree FV. The values measured from both right and left eyes were combined to obtain a single value to compensate for the effect of head tilt during measurement. A total of 86 full-term and 145 preterm children were enrolled in this study. The DFAs measured using OCT and CFP were -11.57° ± 5.27° and -12.07° ± 5.66° in the full-term group and -10.64° ± 5.40° and -11.25° ± 4.80° in the preterm group, respectively. There were no significant differences between the results obtained from OCT and CFP in the two groups (=0.109 and =0.512, respectively). There was a strong correlation between OCT and CFP in all patients, with a Pearson's correlation coefficient of 0.74 and an intraclass correlation coefficient (ICC) of 0.74 (both < 0.001). Multivariate regression analysis showed that the average axial length (AXL) was associated with DFA. This study found a significant correlation between DFA measured using OCT and CFP, making either measurement modality feasible in pediatric populations. There was no significant difference in the DFA between full-term and preterm children. AXL demonstrated an association with the DFA.
本研究旨在比较眼扭转测量结果，以调查健康足月儿和早产儿群体的正常客观旋转性眼扭转值。参与本研究的受试者年龄范围为3至12岁，分为两组，即足月儿（胎龄（GA）>37周）和无早产儿视网膜病变（ROP）的早产儿（GA≤37周）。使用两种不同的成像方式，即视野为55度的光学相干断层扫描（OCT）和视野为45度的传统眼底摄影（CFP），通过视盘中心-黄斑中心凹角（DFA）来评估眼扭转。将左右眼测量的值合并以获得单个值，以补偿测量过程中头部倾斜的影响。本研究共纳入86名足月儿和145名早产儿。足月儿组使用OCT和CFP测量的DFA分别为-11.57°±5.27°和-12.07°±5.66°，早产儿组分别为-10.64°±5.40°和-11.25°±4.80°。两组中OCT和CFP的结果之间均无显著差异（分别为=0.109和=0.512）。所有患者中OCT和CFP之间存在强相关性，Pearson相关系数为0.74，组内相关系数（ICC）为0.74（均<0.001）。多变量回归分析显示，平均眼轴长度（AXL）与DFA相关。本研究发现，使用OCT和CFP测量的DFA之间存在显著相关性，这使得两种测量方式在儿科人群中均可行。足月儿和早产儿的DFA无显著差异。AXL与DFA存在关联。
