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澳大利亚一项家庭调查中γ-羟基丁酸(GHB)和氯胺酮使用情况的流行病学调查

The epidemiology of GHB and ketamine use in an Australian household survey.

作者信息

Degenhardt Louisa, Dunn Matthew

机构信息

National Drug and Alcohol Research Centre, University of NSW, Sydney, NSW 2052, Australia.

出版信息

Int J Drug Policy. 2008 Aug;19(4):311-6. doi: 10.1016/j.drugpo.2007.08.007. Epub 2007 Oct 24.

Abstract

BACKGROUND

There have been apparent increases in recent years in the illicit use of ketamine and gamma-hydroxybutyrate (GHB), but to date there has been no examination of the epidemiology of use in the general population. This paper provides the first such Australian data on the patterns and correlates of GHB and ketamine use.

METHOD

Data were analysed from the 2004 National Drug Strategy Household Survey, a multistage probability sample of Australians aged 14 years or older. Associations between GHB and ketamine use, and core demographic and other drug use variables, were examined.

RESULTS

0.5% of Australians aged 14 years or older reported ever using GHB, and 0.1% reported recent use, with the prevalence of use being highest amongst those aged 20-29 years. Lifetime use of ketamine was reported by 1% of Australians aged 14 years or older, with 0.3% reporting recent use. Again, prevalence of ketamine use was highest amongst those aged 20-29 years. Those who reported ever using these drugs described a pattern of occasional use, with the large majority not using these drugs in the past year. Multiple regression analyses suggested that compared to non-users, GHB and ketamine users were more likely to report the recent use of a wide range of other drugs.

CONCLUSIONS

The prevalence of GHB and ketamine use in Australia appears to be quite low. The present study found high rates of polydrug use, as have been documented in convenience samples of GHB and ketamine users in previous work. As for other illegal drugs used by small proportions of the population, detailed data on patterns of use and associated risks of use are probably best derived from targeted samples of users; household survey data allow comparisons of the relative prevalence of use compared to other illicit drugs and future work will provide the opportunity to consider changes in the extent of use in the general population.

摘要

背景

近年来,氯胺酮和γ-羟基丁酸(GHB)的非法使用明显增加,但迄今为止,尚未对普通人群的使用流行病学进行研究。本文提供了澳大利亚关于GHB和氯胺酮使用模式及相关因素的首批此类数据。

方法

对2004年全国药物战略家庭调查的数据进行分析,该调查是对14岁及以上澳大利亚人的多阶段概率抽样。研究了GHB和氯胺酮使用与核心人口统计学及其他药物使用变量之间的关联。

结果

14岁及以上的澳大利亚人中有0.5%报告曾使用过GHB,0.1%报告近期使用过,使用率在20至29岁人群中最高。14岁及以上的澳大利亚人中有1%报告曾使用过氯胺酮,0.3%报告近期使用过。同样,氯胺酮使用率在20至29岁人群中最高。那些报告曾使用过这些药物的人描述的是偶尔使用模式,绝大多数人在过去一年未使用过这些药物。多元回归分析表明,与未使用者相比,GHB和氯胺酮使用者更有可能报告近期使用过多种其他药物。

结论

澳大利亚GHB和氯胺酮的使用率似乎相当低。本研究发现多药滥用率很高,正如之前研究中GHB和氯胺酮使用者的便利样本所记录的那样。对于其他小比例人群使用的非法药物,关于使用模式和相关使用风险的详细数据可能最好从目标使用者样本中获取;家庭调查数据有助于比较与其他非法药物相比的相对使用率,未来的研究将提供机会来考虑普通人群使用程度的变化。

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