Wu Li-Tzy, Pilowsky Daniel J, Schlenger William E
Center for Risk Behavior and Mental Health Research, RTI International, 3040 Cornwallis Road, Research Triangle Park, NC 27709-2194, USA.
Drug Alcohol Depend. 2005 Apr 4;78(1):23-32. doi: 10.1016/j.drugalcdep.2004.08.025.
We examined the association between the use of inhalants, marijuana, and other drugs and recent DSM-IV substance use disorders among adolescents aged 12-17 years.
Data were drawn from 2000 to 2001 National Household Surveys on Drug Abuse. Adolescents aged 12-17 years who reported having ever used an illicit drug in their lifetime were categorized into four mutually exclusive groups: inhalant users (16%), marijuana users (53%), inhalant and marijuana users (16%), and other drug users (15%). Logistic regression models were used to estimate associations with recent substance use diagnoses among lifetime adolescent drug users (N=10,180).
We found that 31% of lifetime drug users reported having never used marijuana. One half of these atypical drug users were predominantly nonmedical users of pain relievers. Adolescents who used inhalants or other drugs but not marijuana were least likely to report multidrug use. Adolescents who reported using both inhalants and marijuana were most likely to use three or more classes of drugs (73%) and to receive a diagnosis of past year alcohol (35%) and drug (39%) abuse or dependence.
Our study findings suggest that among lifetime adolescent drug users, those who use both inhalants and marijuana are at very high risk for alcohol and drug use disorders.
我们研究了吸入剂、大麻及其他药物的使用与12至17岁青少年近期的《精神疾病诊断与统计手册》第四版(DSM-IV)物质使用障碍之间的关联。
数据取自2000年至2001年全国药物滥用家庭调查。报告一生中曾使用过非法药物的12至17岁青少年被分为四个相互排斥的组:吸入剂使用者(16%)、大麻使用者(53%)、吸入剂和大麻使用者(16%)以及其他药物使用者(15%)。使用逻辑回归模型来估计与终生青少年药物使用者(N = 10,180)近期物质使用诊断之间的关联。
我们发现,31%的终生药物使用者报告从未使用过大麻。这些非典型药物使用者中有一半主要是止痛药的非医疗使用者。使用吸入剂或其他药物但不使用大麻的青少年报告多药使用的可能性最小。报告同时使用吸入剂和大麻 的青少年最有可能使用三类或更多类药物(73%),并被诊断为过去一年有酒精(35%)和药物(39%)滥用或依赖。
我们的研究结果表明,在终生青少年药物使用者中,同时使用吸入剂和大麻的人患酒精和药物使用障碍的风险非常高。