Temmar Mohamed, Labat Carlos, Benkhedda Salim, Charifi Meriem, Thomas Frederique, Bouafia Mohamed Tahar, Bean Kathy, Darne Bernadette, Safar Michel E, Benetos Athanase
Cardiology Centre, Ghardaia, Algeria.
J Hypertens. 2007 Nov;25(11):2218-26. doi: 10.1097/HJH.0b013e3282dc7549.
In-Salah is a city-oasis located in the middle of the Algerian Sahara, a desert area whose drinking water has a high sodium content. No cardiovascular epidemiological studies have ever been conducted in this region.
A randomized sample of 635 men and 711 women, aged 40-99 years, was studied. Blood pressure measurements, combined with a clinical questionnaire that included educational and socio-economic data, and standard blood samples for the detection of dyslipidemia and diabetes mellitus, were collected.
The mean age was 55 +/- 12 years. The prevalence of hypertension was 44% and was highly influenced by age, sex, skin colour, educational status, obesity and metabolic parameters. The higher prevalence of hypertension among black individuals was independent of socio-economic and educational levels, and of metabolic parameters. The presence of antihypertensive treatment was three times more frequent in women than in men, and there was no difference according to skin colour. Among treated subjects, 25% were well controlled, and this percentage was similar among both black and white individuals.
Epidemiological studies in such an emergent population indicate that hypertension is a major public health problem. The high sodium content in drinking water in this region could play a major role in the development of hypertension.
因萨拉赫是位于阿尔及利亚撒哈拉沙漠中部的一座城市绿洲，该沙漠地区的饮用水钠含量很高。此前从未在该地区开展过心血管流行病学研究。
对635名年龄在40至99岁之间的男性和711名同龄女性进行随机抽样研究。收集了血压测量数据、一份包含教育和社会经济数据的临床问卷，以及用于检测血脂异常和糖尿病的标准血样。
平均年龄为55±12岁。高血压患病率为44%，且受年龄、性别、肤色、教育程度、肥胖和代谢参数的影响很大。黑人中较高的高血压患病率与社会经济和教育水平以及代谢参数无关。接受降压治疗的女性比男性多两倍，且按肤色划分无差异。在接受治疗的人群中，25%的患者血压得到良好控制，黑人和白人中的这一比例相似。
对这类新兴人群的流行病学研究表明，高血压是一个主要的公共卫生问题。该地区饮用水中的高钠含量可能在高血压的发生中起主要作用。
