Kobayashi K A, Lui H, Prendiville J S
British Columbia Children's Hospital, Vancouver, Canada.
Pediatr Dermatol. 1991 Dec;8(4):292-5. doi: 10.1111/j.1525-1470.1991.tb00936.x.
A 5-year-old girl had a solitary sclerotic plaque on the back of recent onset. The histopathologic features were consistent with morphea profunda. Thickening and homogenization of collagen bundles were demonstrated in the dermis and subcutaneous tissues, admixed with a prominent lymphocytic and plasma cell inflammatory infiltrate. Solitary morphea profunda is a variant of localized scleroderma that has not been reported previously in childhood. Cases described in the literature as nodular or keloid morphea may represent a similar entity.
一名5岁女童近期在背部出现一个孤立性硬化斑块。组织病理学特征符合深部硬斑病。真皮和皮下组织中可见胶原束增厚和均质化，伴有显著的淋巴细胞和浆细胞炎性浸润。孤立性深部硬斑病是局限性硬皮病的一种变异型，此前在儿童中未见报道。文献中描述为结节性或瘢痕疙瘩样硬斑病的病例可能代表类似的疾病实体。
