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[面部疼痛的治疗]

[Therapy of facial pain].

作者信息

Schuh-Hofer S, Arnold G

机构信息

Klinik für Allgemeine Neurologie, Universitätsklinikum Tübingen, Tübingen.

出版信息

Dtsch Med Wochenschr. 2007 Oct;132(41):2149-52. doi: 10.1055/s-2007-985655.

Abstract

Facial pain is a rare and often misdiagnosed condition. The most common facial pain syndrome is trigeminal neuralgia (TG), which is characterized by paroxysms of excruciating, sharp, burning or lancinating pain. Most cases are caused by a vascular compression of the trigeminal nerve at its entry zone to the pons. Treatment strategies comprise medical treatment and surgical procedures. Anticonvulsants like carbamazepin or gabapentin are widely used for the treatment of TG. The decision on the individual drug therapy may depend on factors like pharmacokinetic properties and individual drug tolerability. In case of drug failure, surgical treatment options like microvascular decompression are available. Persistent idiopathic facial pain is a rare pain condition. Elaborate diagnostic investigations have to be performed since symptomatic causes may be overlooked. Antidepressant drugs like amitriptyline are the first-line drugs for the treatment of this condition.

摘要

面部疼痛是一种罕见且常被误诊的病症。最常见的面部疼痛综合征是三叉神经痛(TG),其特征为阵发性剧痛、锐痛、灼痛或刺痛。大多数病例是由三叉神经在进入脑桥的区域受到血管压迫所致。治疗策略包括药物治疗和外科手术。像卡马西平或加巴喷丁这样的抗惊厥药被广泛用于治疗三叉神经痛。个体药物治疗方案的决定可能取决于药代动力学特性和个体药物耐受性等因素。若药物治疗失败,可采用微血管减压等外科治疗方法。持续性特发性面部疼痛是一种罕见的疼痛病症。由于可能会忽略有症状的病因,所以必须进行详尽的诊断性检查。像阿米替林这样的抗抑郁药是治疗这种病症的一线药物。

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