Köling A
Oron-, näs-och halskliniken, Akademiska sjukhuset, Uppsalsa.
Lakartidningen. 1998 May 13;95(20):2320-5.
Pain is a major public health problem. The management of orofacial pain may be a difficult challenge to the medical and dental professions. Ideally, severe cases of this type of pain should be treated by a team drawn from several disciplines such as neurology, otolaryngology, dentistry and psychiatry. Trigeminal neuralgia patients develop brief, very severe unilateral pain, usually radiating from the upper or lower jaw toward the ear, and confined to the distribution of the trigeminal nerve. The pain may be triggered by chewing, shaving or exposure to cold wind. Most patients respond to carbamazepine, with phenytoin or baclofen as an alternative. Intractable pain may require surgical treatment. Horton's syndrome (cluster headache) is always unilateral and is often associated with unilateral lacrimation and rhinorrhoea. The pain is extreme, and its typical localisation the eye, forehead, temple, jaws, or teeth. Treatment with ergotamine and sumatriptan has been used with some success, calcium blockers (e.g., verapamil) being used as prophylaxis. Atypical facial pain is a continuous ache with intermittent episodes, localised to non-muscular, non-joint facial areas. The pain may be unilateral or bilateral, and may persist for many years. Typically, these patients consult a variety of specialists, such as dentists and otolaryngologists. Surgical procedures such as tooth extraction or sinus surgery, even if skillfully executed, exacerbate the condition, are are thus contraindicated. If the patient does not respond to reassurance, antidepressants may be tried. In sinusitis, the pain location is dependent upon which paranasal sinus is affected. Routine diagnostic nasal endoscopy and coronal plane computed tomography enable subtle pathological changes that are related to chronic pain to be identified. If medical treatment fails to afford relief, surgery should be considered. Pain, limited range of jaw motion, and joint noises are the common characteristics of temporomandibular disorders. Treatment usually consists of non-surgical means such as splints, occlusal equilibration, and non-steroidal anti-inflammatory drugs. Surgical treatment is indicated in a few carefully selected cases. Most dental pain is attributable to caries or periodontal disease. When pus is present, drainage affords excellent pain relief. Acute pericoronitis involving mandibular third molars responds to irrigation, removal of maxillary third molar trauma, and--in cases of serious infection--antimicrobial therapy. Early recognition of a case of chronic pain improves the chances of successful management, and avoids frustration and disillusion both to patient and doctor.
疼痛是一个重大的公共卫生问题。口腔面部疼痛的管理对医学和牙科专业来说可能是一项艰巨的挑战。理想情况下,这类严重疼痛病例应由来自神经学、耳鼻喉科、牙科和精神病学等多个学科的团队进行治疗。三叉神经痛患者会出现短暂、非常严重的单侧疼痛,通常从上下颌向耳部放射,并局限于三叉神经的分布区域。疼痛可能由咀嚼、剃须或暴露于冷风引发。大多数患者对卡马西平有反应,也可选用苯妥英钠或巴氯芬作为替代。顽固性疼痛可能需要手术治疗。霍顿综合征(丛集性头痛)总是单侧的,常伴有单侧流泪和流涕。疼痛剧烈,典型部位为眼睛、前额、颞部、颌部或牙齿。使用麦角胺和舒马曲坦治疗取得了一定成功,钙通道阻滞剂(如维拉帕米)用作预防用药。非典型面部疼痛是一种持续的隐痛,伴有间歇性发作,局限于非肌肉、非关节的面部区域。疼痛可能是单侧或双侧的,可能持续多年。通常,这些患者会咨询各种专科医生,如牙医和耳鼻喉科医生。诸如拔牙或鼻窦手术等外科手术,即使操作熟练,也会使病情加重,因此是禁忌的。如果患者对安慰治疗无反应,可以尝试使用抗抑郁药。在鼻窦炎中,疼痛部位取决于受影响的鼻窦。常规诊断性鼻内镜检查和冠状面计算机断层扫描能够识别与慢性疼痛相关的细微病理变化。如果药物治疗无法缓解,应考虑手术治疗。疼痛、下颌运动范围受限和关节弹响是颞下颌关节紊乱的常见特征。治疗通常包括非手术方法,如使用夹板、咬合平衡调整和非甾体类抗炎药。在少数经过精心挑选的病例中才考虑手术治疗。大多数牙痛归因于龋齿或牙周病。有脓液时,引流可有效缓解疼痛。涉及下颌第三磨牙的急性冠周炎通过冲洗、拔除上颌第三磨牙创伤,以及在严重感染情况下进行抗菌治疗来缓解。早期识别慢性疼痛病例可提高成功治疗的几率,并避免患者和医生的沮丧与失望。