Sternitzky R, Hänsgen K, Podhaisky H
Klinik und Poliklinik für Innere Medizin, Martin-Luther-Universität Halle-Wittenberg.
Z Gesamte Inn Med. 1991 Nov;46(16):610-4.
Microcirculatory disturbances are important complications in hypertension, arterial occlusive disease (PAVK) and diabetic angiopathies. The special haemorrheological diagnostics for the judgment of the terminal vascular bed tended to the comprehension of the haemorheological risk. Due to the increase of the aggregation of erythrocytes and viscosity of the plasma in peripheral arterial occlusive disease and diabetic angiopathies this risk proved to be distinctly increased, in diabetes mellitus without vascular complications and essential arterial hypertension it proved less distinctly increased. In hypertension the application of diuretic drugs should be done more critically and more controlled, in order to avoid conditions of hyperviscosity with their sequels for the microcirculation. The internal therapy in PAVK and diabetic angiopathies must include the amelioration of the disturbed blood fluidity.
微循环障碍是高血压、动脉闭塞性疾病(外周动脉血管疾病)和糖尿病血管病变的重要并发症。用于判断末梢血管床的特殊血液流变学诊断有助于理解血液流变学风险。由于外周动脉闭塞性疾病和糖尿病血管病变中红细胞聚集增加和血浆粘度升高,这种风险明显增加,在无血管并发症的糖尿病和原发性高血压中,这种风险增加不太明显。在高血压中,利尿剂的应用应更加谨慎并加以控制,以避免高粘度状态及其对微循环的后续影响。外周动脉血管疾病和糖尿病血管病变的内科治疗必须包括改善紊乱的血液流动性。