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[心脏瓣膜假体功能障碍的外科治疗经验。55例报告]

[Medico-surgical experience in dysfunction of heart valve prostheses. Report of 55 cases].

作者信息

Astudillo R, González V M, Lara R, Farell J, Ariza H

机构信息

Hospital de Cardiología, Luis Méndez, Centro Médico siglo XXI. IMSS, México, D.F.

出版信息

Arch Inst Cardiol Mex. 1991 Nov-Dec;61(6):549-52.

PMID:1793307
Abstract

The medical and surgical outcome of 55 patients with prosthetic valve disfunction are reported (39 bioprosthesis and 16 mechanical). Fifty patients were operated and five had medical treatment. The group of patients with mechanical prosthesis had a functional class of 2.4 +/- .74 vs patients with bioprosthesis who had a functional class of 2.8 +/- .71. Forty eight patients (87%) had congestive heart failure, four systemic emboli and three infective endocarditis. Three cases with mechanical prosthesis in tricuspid position were subjected to thrombolysis with streptokinase and experienced clinical and echocardiographical improvement. Time elapsed from original implantation and valve disfunction was 66 +/- 56 months for mechanical prosthesis vs 108 +/- 37 months in bioprosthesis (p less than 0.01), three patients died at surgery and two during the waiting period. All deaths resulted from cardiogenic shock. All of them were previously on functional class IV.

摘要

报告了55例人工瓣膜功能障碍患者的内科及外科治疗结果(39例生物瓣和16例机械瓣)。50例接受了手术,5例接受了内科治疗。机械瓣患者的功能分级为2.4±0.74,而生物瓣患者的功能分级为2.8±0.71。48例患者(87%)有充血性心力衰竭,4例发生系统性栓塞,3例发生感染性心内膜炎。3例三尖瓣位置机械瓣患者接受了链激酶溶栓治疗,临床及超声心动图检查均有改善。从最初植入到瓣膜功能障碍的时间,机械瓣为66±56个月,生物瓣为108±37个月(p<0.01),3例患者手术时死亡,2例在等待期死亡。所有死亡均由心源性休克导致。他们之前均为功能分级IV级。

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