Klinkosz Tomasz, Lewa Czeslaw J, Paczkowski Jacek
Institute of Experimental Physics, University of Gdańsk, Gdańsk, Poland.
Ultrasound Med Biol. 2008 Feb;34(2):265-75. doi: 10.1016/j.ultrasmedbio.2007.07.005. Epub 2007 Oct 23.
The aim of our research was to measure and analyze phase velocity and pulse attenuation of a shear wave in two media: well-known agarose-gelatin gel and seldom-used polyacrylamide gel. These quantities were determined at three temperatures by the method of transmission sonoelastography described by Catheline et al. (1999). The shear wave was generated with a shaker stimulated by an electric pulse, with a length of one sinusoidal period with a preset frequency. The calculation method is based on a cross-correlation algorithm used for consecutive A-scans of signals of backwards scattered ultrasonic pulses. It allows determination of the local displacement of scattering elements in the medium, caused by a propagating shear wave, and determination of viscoelastic properties of gels. The results of the measurements of shear wave phase velocity and attenuation, obtained for agarose-gelatin and polyacrylamide gels that simulate biological systems depending on frequency and amplitude of vibrations, are presented. The comparison of the measured characteristic properties of gels has revealed that polyacrylamide gel is more useful in viscoelastic investigations of tissue-like phantoms.
著名的琼脂糖 - 明胶凝胶和较少使用的聚丙烯酰胺凝胶。这些量是通过卡特琳等人(1999年)描述的透射超声弹性成像方法在三个温度下测定的。剪切波由受电脉冲刺激的振动器产生,其长度为具有预设频率的一个正弦周期。计算方法基于用于对反向散射超声脉冲信号进行连续A扫描的互相关算法。它可以确定由传播的剪切波引起的介质中散射元件的局部位移,并确定凝胶的粘弹性特性。本文给出了针对模拟生物系统的琼脂糖 - 明胶和聚丙烯酰胺凝胶,根据振动频率和幅度获得的剪切波相速度和衰减的测量结果。对凝胶测量特性的比较表明,聚丙烯酰胺凝胶在类组织体模的粘弹性研究中更有用。