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球部端端吻合术的长期随访:单中心153例患者的回顾性分析

Long-term followup of bulbar end-to-end anastomosis: a retrospective analysis of 153 patients in a single center experience.

作者信息

Barbagli Guido, De Angelis Michele, Romano Giuseppe, Lazzeri Massimo

机构信息

Center for Urethral Reconstructive Surgery, Arezzo, Italy.

出版信息

J Urol. 2007 Dec;178(6):2470-3. doi: 10.1016/j.juro.2007.08.018. Epub 2007 Oct 15.

Abstract

PURPOSE

We performed a retrospective evaluation and statistical analysis of outcome in patients who underwent bulbar end-to-end anastomosis.

MATERIALS AND METHODS

We reviewed 153 patients with an average age of 39 years who underwent bulbar end-to-end anastomosis between 1988 and 2006. Mean followup was 68 months. Stricture etiology was unknown (62.7%), catheter (14.4%), blunt perineal trauma (11.7%), instrumentation (9.8%), radiotherapy (0.7%) and infection (0.7%). Stricture length was 1 to 2 cm (in 59.5%), 2 to 3 cm (37.9%), 3 to 4 cm (1.9%) or 4 to 5 cm (0.7%). A total of 90 patients (59%) underwent dilation, internal urethrotomy, urethroplasty or multiple procedures before being referred to our center. Clinical outcome was considered a treatment failure when any postoperative instrumentation was needed. The prevalence of postoperative sexual dysfunction was investigated using a nonvalidated questionnaire.

RESULTS

Of 153 cases 139 (90.8%) were successful and 14 (9.2%) were treatment failures. Treatment failure was managed with urethrotomy in 9 cases, end-to-end anastomosis in 2, buccal mucosal graft urethroplasty in 1 and 2-stage repair in 2. Of 14 cases of failure 12 had a satisfactory final outcome, 1 is still waiting for the second stage of urethroplasty and 1 underwent definitive perineostomy. There were 14 patients (23.3%) who experienced ejaculatory dysfunction, 1 (1.6%) a cold glans during erection, 7 (11.6%) a glans that was neither full nor swollen during erection and 11 (18.3%) had decreased glans sensitivity. No patients complained of penile chordee or impotence.

CONCLUSIONS

Bulbar end-to-end anastomosis has a success rate of 90.8%. Most patients were satisfied with the surgical outcome despite postoperative complications such as ejaculatory dysfunction, a glans that was neither full nor swollen during erection, or decreased penile sensitivity.

摘要

目的

我们对接受球部端端吻合术的患者的治疗结果进行了回顾性评估和统计分析。

材料与方法

我们回顾了1988年至2006年间接受球部端端吻合术的153例患者,平均年龄39岁。平均随访时间为68个月。狭窄病因不明(62.7%)、导尿管相关(14.4%)、钝性会阴部创伤(11.7%)、器械操作(9.8%)、放疗(0.7%)及感染(0.7%)。狭窄长度为1至2cm(59.5%)、2至3cm(37.9%)、3至4cm(1.9%)或4至5cm(0.7%)。共有90例患者(59%)在转诊至我们中心之前接受了扩张、内尿道切开术、尿道成形术或多种手术。当术后需要任何器械操作时,临床结果被视为治疗失败。使用一份未经验证的问卷调查术后性功能障碍的发生率。

结果

153例患者中,139例(90.8%)成功,14例(9.2%)治疗失败。9例治疗失败患者接受了尿道切开术,2例接受了端端吻合术,1例接受了颊黏膜移植尿道成形术,2例接受了二期修复。14例失败患者中,12例最终结果满意,1例仍在等待尿道成形术的第二阶段,1例接受了确定性会阴造口术。有14例患者(23.3%)出现射精功能障碍,1例(1.6%)勃起时龟头发凉,7例(11.6%)勃起时龟头既不饱满也不肿胀,11例(18.3%)龟头敏感性降低。没有患者抱怨阴茎弯曲或阳痿。

结论

球部端端吻合术的成功率为90.8%。尽管术后存在射精功能障碍、勃起时龟头既不饱满也不肿胀或阴茎敏感性降低等并发症,但大多数患者对手术结果满意。

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