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采用增强型罗素背侧条带吻合术一期修复长段球部尿道狭窄:234例患者的治疗结果

One-stage repair of long bulbar urethral strictures using augmented Russell dorsal strip anastomosis: outcome of 234 cases.

作者信息

El-Kassaby Abdel W, El-Zayat Tarek M, Azazy Samir, Osman Tarek

机构信息

Department of Urology, University of Ain-Shams, Cairo, Egypt.

出版信息

Eur Urol. 2008 Feb;53(2):420-4. doi: 10.1016/j.eururo.2007.06.002. Epub 2007 Jun 11.

Abstract

OBJECTIVES

Long bulbar urethral strictures (>2 cm) are not amenable to stricture excision and primary anastomosis procedure, which may result in a short urethra and chordee formation. For such strictures many procedures have been advocated including stricturotomy with subsequent graft or flap onlay, augmented anastomosis, and staged procedures, which is a combination of the Russell graft. We present our 10-yr experience with the augmented Russell procedure using a ventral onlay buccal mucosal patch graft for treatment of long bulbar urethral strictures not amenable to excision and primary anastomosis.

METHODS

A total of 234 patients diagnosed by urethrograms as having long bulbar urethral strictures (mean, 4.2 cm) were managed by the augmented Russell urethroplasty. The procedure included excision of most of the diseased segment (mean, 2.8 cm) and anastomosis of a dorsal strip leaving an oval ventral defect. Augmentation was done in all patients using a buccal mucosa patch graft (mean, 4.7 cm).

RESULTS

Mean follow-up was 36 mo. Urethrograms were done at 3 wk and 3 and 6 mo postoperatively and if the patients were symptomatic thereafter. Urethrocystoscopy was performed at 12 and 18 mo. A total of 223 patients completed the follow-up protocol; the overall success rate was 93.7% with 14 (6.3%) patients showing stricture recurrence at different intervals postoperatively. Ten patients in the failure group were successfully managed by single visualized internal urethrotomy (VIU), whereas the other four patients were treated by ventral penile pedicled flap. Postoperative dribbling of urine was noticed by 90 patients (40.4%) and temporary perioral numbness in most patients; no major donor site complications were noted in our series.

CONCLUSION

The augmented Russell technique is beneficial for long bulbar urethral strictures; 93.7% of the patients were stricture free. In the bulbar region, both ventral and dorsal onlays are applicable with nearly equal success rates. The buccal mucosa patch graft offers excellent material for augmentation.

摘要

目的

长段球部尿道狭窄(>2 cm)不适用于狭窄切除及一期吻合术,该手术可能导致尿道缩短和阴茎下弯形成。针对此类狭窄,已提出多种手术方法,包括狭窄切开术并随后进行移植或皮瓣覆盖、扩大吻合术以及分期手术,后者是Russell移植术的一种组合。我们介绍了采用腹侧覆盖颊黏膜补片移植的改良Russell手术治疗不适用于切除及一期吻合的长段球部尿道狭窄的10年经验。

方法

共有234例经尿道造影诊断为长段球部尿道狭窄(平均4.2 cm)的患者接受了改良Russell尿道成形术。手术包括切除大部分病变段(平均2.8 cm),并吻合一条背侧条带,留下椭圆形腹侧缺损。所有患者均使用颊黏膜补片移植(平均4.7 cm)进行扩大修复。

结果

平均随访36个月。术后3周、3个月和6个月以及之后患者出现症状时进行尿道造影。术后12个月和18个月进行尿道膀胱镜检查。共有223例患者完成随访方案;总体成功率为93.7%,14例(6.3%)患者在术后不同时间出现狭窄复发。失败组中的10例患者通过单次可视内部尿道切开术(VIU)成功治疗,而其他4例患者接受了腹侧阴茎带蒂皮瓣治疗。90例患者(40.4%)术后出现尿滴沥,大多数患者出现暂时性口周麻木;本系列中未发现严重的供区并发症。

结论

改良Russell技术对长段球部尿道狭窄有益;93.7%的患者无狭窄。在球部区域,腹侧和背侧覆盖均适用,成功率相近。颊黏膜补片移植为扩大修复提供了优质材料。

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