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[术前功能和疼痛对全髋关节置换术后以患者为中心的早期结局的影响]

[The impact of preoperative function and pain on early patient-centred outcome after total hip arthroplasty].

作者信息

Kessler S, Mattes T, Cakir B, Reichel H, Käfer W

机构信息

Orthopädische Abteilung, Krankenhaus Sindelfingen.

出版信息

Z Orthop Unfall. 2007 Sep-Oct;145(5):563-7. doi: 10.1055/s-2007-965668.

Abstract

AIM

It was the purpose of this prospective study to investigate the impact of preoperative functional status and pain on the early patient-centred outcome after total hip arthroplasty (THA).

METHODS

67 consecutive patients scheduled for THA were included in this study. Outcome was analysed with the Western Ontario and McMaster Universities' (WOMAC) Osteoarthritis Index preoperatively and after ten days and 12 weeks, respectively. Patients were grouped with regard to their preoperative function and pain according to the WOMAC Osteoarthritis Index. Statistical analysis was performed using a multivariate regression model considering further confounding variables (age, gender, affected side, duration of surgery, and anchorage of THA).

RESULTS

All patients showed a significant functional improvement both at ten days postoperatively and after three months, respectively. Patients with a higher degree of disability preoperatively had a larger relative functional improvement according to their WOMAC score compared to patients who initially were less deteriorated. However, the latter had the better absolute scores postoperatively. Multiple regression analysis revealed gender (OR: -11.85, 95% CI: -22.65 to -1.06, p=0.03) and preoperative WOMAC score (OR: 0.34, 95% CI: 0.09 to 0.59, p<0.01) to be significant prognostic variables at ten days postoperatively. After three months, age (OR: 0.43, 95% CI: 0.04 to 0.82, p=0.03) was the only variable predicting the patient-centred outcome.

CONCLUSION

In our study sample, patient-related variables did significantly influence the patient-centred outcome after ten days (gender and WOMAC) and at three months postoperatively (age) whereas procedure-related variables did not have any impact.

摘要

目的

本前瞻性研究旨在调查术前功能状态和疼痛对全髋关节置换术(THA)后以患者为中心的早期结局的影响。

方法

本研究纳入了67例连续计划接受THA的患者。分别在术前、术后10天和12周使用西安大略和麦克马斯特大学(WOMAC)骨关节炎指数分析结局。根据WOMAC骨关节炎指数,将患者按术前功能和疼痛情况进行分组。使用多变量回归模型进行统计分析,同时考虑其他混杂变量(年龄、性别、患侧、手术时间和THA的固定方式)。

结果

所有患者在术后10天和三个月时功能均有显著改善。与最初病情较轻的患者相比,术前残疾程度较高的患者根据其WOMAC评分相对功能改善更大。然而,后者术后的绝对评分更好。多变量回归分析显示,术后10天时性别(OR:-11.85,95%CI:-22.65至-1.06,p=0.03)和术前WOMAC评分(OR:0.34,95%CI:0.09至0.59,p<0.01)是显著的预后变量。三个月后,年龄(OR:0.43,95%CI:0.04至0.82,p=0.03)是唯一预测以患者为中心结局的变量。

结论

在我们的研究样本中,患者相关变量在术后10天(性别和WOMAC)和术后三个月(年龄)时对以患者为中心的结局有显著影响,而手术相关变量没有任何影响。

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