与健康相关的生活质量以及膝关节或髋关节置换的适宜性。
Health-related quality of life and appropriateness of knee or hip joint replacement.
作者信息
Quintana José M, Escobar Antonio, Arostegui Inmaculada, Bilbao Amaia, Azkarate Jesús, Goenaga J Ignacio, Arenaza Juan C
机构信息
Unidad de Investigación, Hospital de Galdakao, Galdakao, Vizcaya, Spain.
出版信息
Arch Intern Med. 2006 Jan 23;166(2):220-6. doi: 10.1001/archinte.166.2.220.
BACKGROUND
We studied the association between explicit appropriateness criteria for total hip joint replacement (THR) and total knee replacement (TKR) with changes in health-related quality of life of patients undergoing these procedures.
METHODS
Prospective observational study of 1576 consecutive patients with diagnoses of osteoarthritis on waiting lists to undergo THR or TKR. Explicit appropriateness criteria using the RAND appropriateness method were applied. Patients completed 2 questionnaires that measured health-related quality of life, the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), before the procedure and 6 months afterward.
RESULTS
Patients who were considered appropriate candidates for these procedures had greater improvements than those who were considered inappropriate candidates in all 3 WOMAC domains (pain, functional limitation, and stiffness; THR: 43.0, 40.6, and 40.4 vs 14.7, 19.1, and 15.9; TKR: 34.9, 32.5, and 30.2 vs 23.2, 18.9, and 17.1; P<.001 for all comparisons). Patients who underwent THR and were judged to be appropriate candidates had greater improvements in the physical function, role-physical, bodily pain, and social function domains of the SF-36 than those judged to be inappropriate candidates (34.4, 35.1, 33.1, and 26.6 vs 19.6, 9.2, 5.7, and 7.0; P = .04, P = .03, P < .001, and P < .001, respectively). Appropriate candidates for TKR demonstrated greater improvement in the social function domain of the SF-36 after the procedure than those deemed inappropriate candidates (19.9 vs 7.9; P = .004) but not in the other domains of functional status.
CONCLUSIONS
These results suggest a direct relationship between explicit appropriateness criteria and better health-related quality-of-life outcomes after THR and TKR surgery. Our results support the use of these criteria for clinical guidelines or evaluation purposes.
背景
我们研究了全髋关节置换术(THR)和全膝关节置换术(TKR)的明确适用性标准与接受这些手术患者健康相关生活质量变化之间的关联。
方法
对1576例在等待名单上被诊断为骨关节炎且即将接受THR或TKR手术的连续患者进行前瞻性观察研究。采用兰德适用性方法应用明确的适用性标准。患者在手术前和术后6个月完成了2份测量健康相关生活质量的问卷,即医学结局研究36项简短健康调查(SF - 36)和西安大略和麦克马斯特大学骨关节炎指数(WOMAC)。
结果
在WOMAC的所有3个领域(疼痛、功能受限和僵硬;THR:43.0、40.6和40.4,而不合适的候选者为14.7、19.1和15.9;TKR:34.9、32.5和30.2,而不合适的候选者为23.2、18.9和17.1;所有比较P <.001),被认为适合这些手术的患者比那些被认为不适合的患者有更大改善。接受THR且被判定为合适候选者的患者在SF - 36的身体功能、角色 - 身体、身体疼痛和社会功能领域的改善比被判定为不合适候选者的患者更大(34.4、35.1、33.1和26.6,而不合适的候选者为19.6、9.2、5.7和7.0;P分别为.04、.03、<.001和<.001)。TKR的合适候选者在手术后SF - 36的社会功能领域比被认为不合适的候选者有更大改善(19.9对7.9;P =.004),但在功能状态的其他领域没有。
结论
这些结果表明明确的适用性标准与THR和TKR手术后更好的健康相关生活质量结果之间存在直接关系。我们的结果支持将这些标准用于临床指南或评估目的。