Kuohung Wendy, Thompson Sharon R, Laufer Marc R
Department of Obstetrics, Boston University School of Medicine, and Brigham and Women's Hospital, Boston, Massachusetts, USA.
J Reprod Med. 2007 Sep;52(9):864-7.
Both autologous and synthetic tissue have been used to create a neovagina in women with Mayer-Rokitansky-Küster-Hauser syndrome. Despite reports on many different techniques, the ideal method of vaginoplasty has not been firmly established.
A 33-year-old woman with Mayer-Rokitansky-Küster-Hauser syndrome had been unsuccessful in using vaginal dilators for the creation of a functional vagina with the Frank technique due to pain and vulvar lichen sclerosis. She thus elected to undergo vaginoplasty by a modified McIndoe procedure using acellular human dermal allograft material. Both the surgery and immediate postoperative course were uncomplicated. Vaginal apex stenosis resulted from inadequate dilatation in the weeks following surgery since the patient experienced pain with dilator use.
The use of dermal allograft material instead of a split-thickness autologous skin graft is a simple and less invasive method of constructing a neovagina. Due to the many potential advantages of this technique, further investigation is warranted to optimize long-term outcomes of vaginoplasty using this method.
自体组织和合成组织均已用于为患有迈耶-罗基坦斯基-库斯特-豪泽综合征的女性构建新阴道。尽管有许多关于不同技术的报道，但理想的阴道成形术方法尚未完全确立。
一名33岁患有迈耶-罗基坦斯基-库斯特-豪泽综合征的女性，因疼痛和外阴苔藓硬化，采用弗兰克技术使用阴道扩张器构建功能性阴道未成功。因此，她选择采用改良的麦金杜手术，使用脱细胞人真皮同种异体移植材料进行阴道成形术。手术及术后即刻过程均无并发症。由于患者使用扩张器时疼痛，术后数周扩张不足导致阴道顶端狭窄。
使用真皮同种异体移植材料而非自体中厚皮片是构建新阴道的一种简单且侵入性较小的方法。鉴于该技术具有诸多潜在优势，有必要进一步研究以优化使用此方法进行阴道成形术的长期效果。
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