Bordelon Yvette M, Smith Marsha
Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Semin Neurol. 2007 Nov;27(5):467-75. doi: 10.1055/s-2007-991128.
Movement disorders are not commonly seen during pregnancy. As a result, there are few studies on whether disease manifestations are affected by the hormonal changes that occur during pregnancy or on the teratogenicity of commonly used medications for movement disorders on the developing fetus. This article discusses movement disorders that are seen only during pregnancy (chorea gravidarum) or that may present during pregnancy (restless legs syndrome), the effect that pregnancy has on symptoms and treatment (in Parkinson's disease, essential tremor, dystonia, tic disorders, and Wilson's disease), and the role of genetic testing for movement disorders in genetic counseling for pregnant women.
运动障碍在孕期并不常见。因此,关于疾病表现是否受孕期激素变化影响,或常用运动障碍药物对发育中胎儿的致畸性,相关研究较少。本文讨论仅在孕期出现的运动障碍(妊娠性舞蹈病)或可能在孕期出现的运动障碍(不宁腿综合征),妊娠对症状及治疗的影响(帕金森病、特发性震颤、肌张力障碍、抽动障碍和肝豆状核变性),以及运动障碍基因检测在孕妇遗传咨询中的作用。