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妊娠期DYT1肌张力障碍的管理

Management of DYT1 dystonia throughout pregnancy.

作者信息

Nageshwaran Sathiji, Nageshwaran Saiji, Edwards Mark J, Morcos Michael

机构信息

University College London, London, UK.

出版信息

BMJ Case Rep. 2011 Sep 4;2011:bcr0520114214. doi: 10.1136/bcr.05.2011.4214.

Abstract

A 30-year-old woman with generalised DYT1 dystonia, controlled with medication, presented at 9 weeks gestation with an unplanned pregnancy. A number of learning points were highlighted in management of the patient's dystonia alongside pregnancy including avoidance of excessive medication exposure to the fetus, while maintaining symptom control to a level acceptable and safe for the patient and prenatal diagnostic testing. In our case there was no overt ill effect to the newborn. This is a common worry among pregnant women with dystonia and as such the authors felt it important to report.

摘要

一名30岁患有全身性DYT1肌张力障碍的女性,通过药物治疗病情得到控制,在妊娠9周时意外怀孕。在该患者孕期肌张力障碍的管理中突出了许多经验教训,包括避免胎儿过度接触药物,同时将症状控制在对患者可接受且安全的水平,并进行产前诊断检测。在我们的病例中,新生儿未出现明显不良影响。这是患有肌张力障碍的孕妇普遍担心的问题,因此作者认为报告此事很重要。

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