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居家锻炼能否改善2型糖尿病患者的体重指数?一项可行性试验的结果。

Does home-based exercise improve body mass index in patients with type 2 diabetes? Results of a feasibility trial.

作者信息

Krousel-Wood M A, Berger L, Jiang X, Blonde L, Myers L, Webber L

机构信息

Ochsner Clinic Foundation, Center for Health Research, New Orleans, LA 70121, United States.

出版信息

Diabetes Res Clin Pract. 2008 Feb;79(2):230-6. doi: 10.1016/j.diabres.2007.08.028. Epub 2007 Oct 17.

Abstract

AIMS

This feasibility trial evaluated the use, safety, and short-term benefits of a home-based exercise intervention designed to increase physical activity among adults with diabetes.

METHODS

Participants with type 2 diabetes in a group practice were recruited and randomly assigned to the home-based exercise intervention or usual care. Participants were given diabetes self-management education, instructed to exercise 30 min 5 days/week, and were followed for 3 months. The intervention contained three exercise routines (aerobic and resistance exercises). Outcomes included changes from baseline at 3 months between groups in body mass index (BMI), quality of life, A1C, and blood pressure.

RESULTS

Seventy-six sedentary adults completed the study: 49% intervention group, 68% women, 47% black, mean age 56.6+/-9.6 years. Using intention to treat analysis, a trend towards improvement between groups for BMI (mean change -0.4 versus 0.1, respectively; P=0.06) was identified. Thirty-eight percent of the intervention group adhered to 80% of the exercise recommendation and significantly improved BMI (-1.07; P<0.05). No other differences were detected between groups.

CONCLUSIONS

Home-based exercise interventions have potential to reduce BMI in patients with diabetes. The results provide variance estimates necessary to power a larger study of longer duration.

摘要

目的

本可行性试验评估了一种旨在增加糖尿病成年患者身体活动量的家庭锻炼干预措施的使用情况、安全性及短期益处。

方法

招募了在团体诊所就诊的2型糖尿病患者,并将其随机分配至家庭锻炼干预组或常规治疗组。给予参与者糖尿病自我管理教育,指导他们每周5天、每天锻炼30分钟,并随访3个月。干预措施包含三种锻炼方案(有氧运动和抗阻运动)。结局指标包括3个月时两组间体重指数(BMI)、生活质量、糖化血红蛋白(A1C)及血压相对于基线的变化。

结果

76名久坐不动的成年人完成了研究:干预组占49%,女性占68%,黑人占47%,平均年龄56.6±9.6岁。采用意向性分析,发现两组间BMI有改善趋势(平均变化分别为-0.4和0.1;P=0.06)。干预组38%的参与者遵循了80%的锻炼建议,且BMI显著改善(-1.07;P<0.05)。两组间未检测到其他差异。

结论

家庭锻炼干预措施有降低糖尿病患者BMI的潜力。研究结果提供了开展更大规模、更长时间研究所需的方差估计值。

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