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2型糖尿病患者每周两次针对性耐力训练的成本节约效果:一项为期一年的对照随机试验。

Cost-sparing effect of twice-weekly targeted endurance training in type 2 diabetics: a one-year controlled randomized trial.

作者信息

Brun J-F, Bordenave S, Mercier J, Jaussent A, Picot M-C, Préfaut C

机构信息

ERI 25, Inserm, 34000 Montpellier, France.

出版信息

Diabetes Metab. 2008 Jun;34(3):258-65. doi: 10.1016/j.diabet.2008.01.010. Epub 2008 May 12.

Abstract

OBJECTIVE

We evaluated the effects of targeted, moderate endurance training on healthcare cost, body composition and fitness in type 2 diabetes patients routinely followed within the French healthcare system.

DESIGN AND METHODS

A total of 25 type 2 diabetic patients was randomly assigned to one of two groups: 13 underwent a training programme (eight sessions, followed by training twice a week for 30-45 minutes at home at the level of the ventilatory threshold [V(T)]); and 12 received their usual routine treatment. Both groups were followed for one year to evaluate healthcare costs, exercise effectiveness and a six-minute walking test.

RESULTS

The training prevented loss of maximum aerobic capacity, which decreased slightly in the untrained group (P=0.014), and resulted in a higher maximum power output (P=0.041) and six-minute walking distance (P=0.020). The Voorrips activity score correlated with both V(O2max) (r=0.422, P<0.05) and six-minute walking distance (r=0.446, P<0.05). Changes in V(O2max) were negatively correlated with changes in body weight (r=0.608, P<0.01). Training decreased the insulin-resistance index (HOMA-IR) by 26% (P<0.05). Changes in percentages of fat were correlated to changes in waist circumference (r=0.436, P<0.05). The total healthcare cost was reduced by 50% in the trained group (euro 1.65+/-1 per day versus euro 3.00+/-1.47 per day in the untrained group; P<0.02) due to fewer hospitalizations (P=0.05) and less use of sulphonylureas (P<0.05).

CONCLUSION

Endurance training at V(T) level prevented the decline in aerobic working capacity seen in untrained diabetics over the study period, and resulted in a marked reduction in healthcare costs due to less treatments and fewer hospitalizations.

摘要

目的

我们评估了针对性的适度耐力训练对法国医疗体系中常规随访的2型糖尿病患者医疗费用、身体成分和体能的影响。

设计与方法

总共25名2型糖尿病患者被随机分为两组:13人接受了一个训练项目(八节课程,随后在家中以通气阈值[V(T)]水平每周训练两次,每次30 - 45分钟);12人接受常规治疗。两组均随访一年以评估医疗费用、运动效果和六分钟步行试验。

结果

训练防止了最大有氧能力的下降,未训练组的最大有氧能力略有下降(P = 0.014),训练组的最大输出功率更高(P = 0.041)且六分钟步行距离更远(P = 0.020)。Voorrips活动评分与最大摄氧量(V(O2max))(r = 0.422,P < 0.05)和六分钟步行距离(r = 0.446,P < 0.05)均相关。V(O2max)的变化与体重变化呈负相关(r = 0.608,P < 0.01)。训练使胰岛素抵抗指数(HOMA - IR)降低了26%(P < 0.05)。脂肪百分比的变化与腰围变化相关(r = 0.436,P < 0.05)。训练组的总医疗费用降低了50%(训练组每天1.65±1欧元,未训练组每天3.00±1.47欧元;P < 0.02),原因是住院次数减少(P = 0.05)和磺脲类药物使用减少(P < 0.05)。

结论

在V(T)水平的耐力训练防止了在研究期间未训练的糖尿病患者有氧工作能力的下降,并由于治疗减少和住院次数减少而导致医疗费用显著降低。

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